Evolution of neuropeptide signalling systems

MR Elphick, O Mirabeau… - Journal of Experimental …, 2018 - journals.biologists.com
Neuropeptides are a diverse class of neuronal signalling molecules that regulate
physiological processes and behaviour in animals. However, determining the relationships …

The long and the short of it–a perspective on peptidergic regulation of circuits and behaviour

G Jékely, S Melzer, I Beets… - Journal of …, 2018 - journals.biologists.com
Neuropeptides are the most diverse class of chemical modulators in nervous systems. They
contribute to extensive modulation of circuit activity and have profound influences on animal …

Graphene field effect transistor-based immunosensor for ultrasensitive noncompetitive detection of small antigens

Y Kanai, Y Ohmuro-Matsuyama, M Tanioku… - ACS …, 2020 - ACS Publications
Due to its high carrier mobility, graphene is considered a suitable material for use in field-
effect transistors. However, its application to immunosensing of small molecules is still …

Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily

F Liu, Y Dang, L Li, H Feng, J Li, H Wang… - Nature Chemical …, 2023 - nature.com
Abstract Phe-Met-Arg-Phe-amide (FMRFamide)-activated sodium channels (FaNaCs) are a
family of channels activated by the neuropeptide FMRFamide, and, to date, the underlying …

[HTML][HTML] New insights from small rhythmic circuits

E Marder, S Kedia, EO Morozova - Current opinion in neurobiology, 2022 - Elsevier
Small rhythmic circuits, such as those found in invertebrates, have provided fundamental
insights into how circuit dynamics depend on individual neuronal and synaptic properties …

Patch-clamp proteomics of single neurons in tissue using electrophysiology and subcellular capillary electrophoresis mass spectrometry

SB Choi, AM Polter, P Nemes - Analytical chemistry, 2021 - ACS Publications
Understanding of the relationship between cellular function and molecular composition
holds a key to next-generation therapeutics but requires measurement of all types of …

BRET Q-body: A ratiometric quench-based bioluminescent immunosensor made of luciferase–dye–antibody fusion with enhanced response

R Takahashi, T Yasuda… - Analytical …, 2021 - ACS Publications
A quenchbody (Q-body) is an immunosensor comprising an antibody fragment containing
an antigen-binding site that is site-specifically labeled with a fluorescent dye. The …

Mass Spectrometry Quantification, Localization, and Discovery of Feeding-Related Neuropeptides in Cancer borealis

K DeLaney, M Hu, T Hellenbrand… - ACS chemical …, 2021 - ACS Publications
The crab Cancer borealis nervous system is an important model for understanding neural
circuit dynamics and modulation, but the identity of neuromodulatory substances and their …

Neuropeptides in Cancer: Friend and Foe?

Y Wu, A Berisha, JC Borniger - Advanced Biology, 2022 - Wiley Online Library
Neuropeptides are small regulatory molecules found throughout the body, most notably in
the nervous, cardiovascular, and gastrointestinal systems. They serve as neurotransmitters …

[HTML][HTML] Capillary electrophoresis coupled to MALDI mass spectrometry imaging with large volume sample stacking injection for improved coverage of C. borealis …

K DeLaney, L Li - Analyst, 2020 - pubs.rsc.org
Neuropeptides are important signaling molecules responsible for a wide range of functions
within the nervous and neuroendocrine system. However, they are difficult to study due to …