Understanding the mechanism of bacterial cGAS immunity and its co-evolution with phage

E Huiting - 2024 - escholarship.org
A fundamental strategy of eukaryotic anti-viral innate immunity involves the cGAS enzyme,
which synthesizes 2', 3'-cGAMP and activates a STING effector to limit viral replication …

The growing repertoire of phage anti-defence systems

K Murtazalieva, A Mu, A Petrovskaya, RD Finn - Trends in Microbiology, 2024 - cell.com
The biological interplay between phages and bacteria has driven the evolution of phage anti-
defence systems (ADSs), which evade bacterial defence mechanisms. These ADSs bind …