Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …

This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

The novel coronavirus disease (COVID-19) outbreak, caused by SARS-CoV-2, represents
the greatest medical challenge in decades. We provide a comprehensive review of the …

The etiology of hypertension involves complex interactions among genetic, environmental,
and pathophysiologic factors that influence many regulatory systems. Hypertension is …

Vascular smooth muscle cells (VSMCs) are the major cell type in blood vessels. Unlike
many other mature cell types in the adult body, VSMC do not terminally differentiate but …

Hypertension is a global public health issue and the leading cause of premature death in
humans. Despite more than a century of research, hypertension remains difficult to cure due …

Arterial remodeling refers to the structural and functional changes of the vessel wall that
occur in response to disease, injury, or aging. Vascular smooth muscle cells (VSMC) play a …

Rationale: Vascular calcification, the formation of calcium phosphate crystals in the vessel
wall, is mediated by vascular smooth muscle cells (VSMCs). However, the underlying …

538 Hypertension September 2018 or near normal LV ejection fractions, consistent with the
clinical picture of HFpEF. In the I-PRESERVE study (Irbesartan in Heart Failure With …

Hypertension is often characterised by impaired vasodilation involving dysfunction of
multiple vasodilatory mechanisms. ω‐3 polyunsaturated fatty acids (PUFAs) …