Chronic obstructive pulmonary disease (COPD), asthma and cystic fibrosis (CF) are distinct
respiratory diseases that share features such as the obstruction of small airways and …

Interleukin 35 (IL-35), a new member of the IL-12 family of heterodimeric cytokines, could
induce two different types of regulatory cells including regulatory T and B cells such as IL-35 …

Objective: To investigate the correlation between systemic immune inflammatory (SII) index,
serum interleukin-35 (IL-35) and high mobility Group-Box one (HMGB-1) with the severity …

Mast cells (MC) are a key effector cell in multiple types of immune responses, including
atopic conditions. Allergic diseases have been steadily rising across the globe, creating a …

The interleukin (IL)-12 family consists of pro-and anti-inflammatory cytokines that are able to
signal the activation of host antiviral immunity while preventing over-reactive immune …

Objective As a member of interleukin-12 family, interleukin-35 (IL-35) plays an important
regulatory role in immune response. The relationship between IL-35 and idiopathic …

Like in many fields of medicine, the concept of precision dosing has re-emerged in routine
practice in allergology. Only one retrospective study on French physicians' practice has …

Background: IL-35 potently inhibits immune responses both in vivo and in vitro. However,
the specific characteristics of IL-35-producing cells, including their developmental origin …

Background Interleukin (IL)-35 has been recently identified as an anti-inflammatory cytokine
in allergic inflammation. However, its biological role in the pathogenesis of allergic rhinitis …

Objective To evaluate the role of induced immunosuppressive T regulatory (iTr) 35 cells in
SSc-related inflammation and fibrosis. Methods Sixty-eight SSc patients were enrolled in this …