[HTML][HTML] Recent advances in ovarian cancer: therapeutic strategies, potential biomarkers, and technological improvements

S Akter, MA Rahman, MN Hasan, H Akhter, P Noor… - Cells, 2022 - mdpi.com
Aggressive and recurrent gynecological cancers are associated with worse prognosis and a
lack of effective therapeutic response. Ovarian cancer (OC) patients are often diagnosed in …

Photoelectrochemical sensors based on paper and their emerging applications in point-of-care testing

Y Wang, Y Rong, T Ma, L Li, X Li, P Zhu, S Zhou… - Biosensors and …, 2023 - Elsevier
Point-of-care testing (POCT) technology is urgently required owing to the prevalence of the
Internet of Things and portable electronics. In light of the attractive properties of low …

[HTML][HTML] Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology

Z Jiwaji, SS Tiwari, RX Avilés-Reyes, M Hooley… - Nature …, 2022 - nature.com
Alzheimer's disease (AD) alters astrocytes, but the effect of Aß and Tau pathology is poorly
understood. TRAP-seq translatome analysis of astrocytes in APP/PS1 ß-amyloidopathy and …

[HTML][HTML] p53 modulation of autophagy signaling in cancer therapies: perspectives mechanism and therapeutic targets

MA Rahman, MN Park, MH Rahman… - Frontiers in cell and …, 2022 - frontiersin.org
The key tumor suppressor protein p53, additionally known as p53, represents an attractive
target for the development and management of anti-cancer therapies. p53 has been …

Functionalised penetrating peptide-chondroitin sulphate‑gold nanoparticles: Synthesis, characterization, and applications as an anti-Alzheimer's disease drug

Y Feng, X Li, D Ji, J Tian, Q Peng, Y Shen… - International Journal of …, 2023 - Elsevier
The purpose of this study was to construct a transmembrane peptide-chondroitin sulphate‑
gold nanoparticle (TAT-CS@ Au) delivery system and investigate its activity as an anti …

mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder

M Perluigi, F Di Domenico, E Barone… - Free Radical Biology and …, 2021 - Elsevier
Alzheimer's disease (AD) is the most prevalent form of dementia in the elderly population
and has worldwide impact. The etiology of the disease is complex and results from the …

A gating mutation in ryanodine receptor type 2 rescues phenotypes of Alzheimer's disease mouse models by upregulating neuronal autophagy

H Zhang, C Knight, SRW Chen… - Journal of …, 2023 - Soc Neuroscience
It is well established that ryanodine receptors (RyanRs) are overactive in Alzheimer's
disease (AD), and it has been suggested that inhibition of RyanR is potentially beneficial for …

[HTML][HTML] Exposure to environmental arsenic and emerging risk of Alzheimer's disease: perspective mechanisms, management strategy, and future directions

MA Rahman, MA Hannan, MJ Uddin, MS Rahman… - Toxics, 2021 - mdpi.com
Alzheimer's disease (AD) is one of the most prevailing neurodegenerative diseases,
characterized by memory dysfunction and the presence of hyperphosphorylated tau and …

[HTML][HTML] Coconut oil as a therapeutic treatment for alzheimer's disease: a review

P Sandupama, D Munasinghe, M Jayasinghe - Journal of Future Foods, 2022 - Elsevier
The coconut tree (Cocos nucifera) which is also known as the “Tree of life” has its own
values in each part of the tree and coconut oil is more prestigious among them. At present …

[HTML][HTML] The multiple roles of autophagy in neural function and diseases

YY Li, ZH Qin, R Sheng - Neuroscience Bulletin, 2024 - Springer
Autophagy involves the sequestration and delivery of cytoplasmic materials to lysosomes,
where proteins, lipids, and organelles are degraded and recycled. According to the way the …