Cancer is the second leading cause of human death globally. PI3K/Akt/mTOR signaling is
one of the most frequently dysregulated signaling pathways observed in cancer patients that …

It is well established that multifactorial drug resistance hinders successful cancer treatment.
Tumor cell interactions with the tumor microenvironment (TME) are crucial in epithelial …

Adrenocortical carcinoma (ACC) is an uncommon aggressive endocrine malignancy that is
nonetheless associated with significant mortality and morbidity rates because of endocrine …

Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …

Oral potentially malignant disorders (OPMD) possess significant chances of malignancy
conversion. In order to develop an early diagnostic tool, the present study evaluated the …

An early diagnosis of hepatocellular carcinoma (HCC) followed by effective treatment is
currently critical for improving the prognosis and reducing the associated economic burden …

We established a genome-wide compendium of somatic mutation events in 3949 whole
cancer genomes representing 19 tumor types. Protein-coding events captured well …

MicroRNA-based therapy that targets cardiac macrophages holds great potential for
treatment of myocardial infarction (MI). Here, we explored whether boosting the miRNA-21 …

RNA tailing, or the addition of non-templated nucleotides to the 3′ end of RNA, is the most
frequent and conserved type of RNA modification. The addition of tails and their composition …

Over the last decades, microRNAs (miRNAs) have emerged as important molecules
associated with the regulation of gene expression in humans and other organisms …