Extracellular vesicle-miRNAs as liquid biopsy biomarkers for disease identification and prognosis in metastatic colorectal cancer patients
D de Miguel Pérez, A Rodriguez Martínez… - Scientific reports, 2020 - nature.com
Disseminated disease is present in≈ 50% of colorectal cancer patients upon diagnosis,
being responsible for most of cancer deaths. Addition of biological drugs, as Bevacizumab …
being responsible for most of cancer deaths. Addition of biological drugs, as Bevacizumab …
Latest trend of milk derived exosomes: Cargos, functions, and applications
X Feng, X Chen, X Zheng, H Zhu, Q Qi, S Liu… - Frontiers in …, 2021 - frontiersin.org
Exosomes are nanosized phospholipid bilayer vesicles released to the extracellular
environment. Exosomes from various tissues or cells are being studied and there has been …
environment. Exosomes from various tissues or cells are being studied and there has been …
The impact of adipose tissue–derived miRNAs in metabolic syndrome, obesity, and cancer
GS Heyn, LH Corrêa, KG Magalhães - Frontiers in endocrinology, 2020 - frontiersin.org
Obesity is a multifactorial and complex condition that is characterized by abnormal and
excessive white adipose tissue accumulation, which can lead to the development of …
excessive white adipose tissue accumulation, which can lead to the development of …
[HTML][HTML] PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells
Aberrant cell proliferation is a hallmark of cancer, including glioblastoma (GBM). Here we
report that protein arginine methyltransferase (PRMT) 6 activity is required for the …
report that protein arginine methyltransferase (PRMT) 6 activity is required for the …
A microRNA signature from serum exosomes of patients with glioma as complementary diagnostic biomarker
A Santangelo, P Imbrucè, B Gardenghi, L Belli… - Journal of neuro …, 2018 - Springer
Malignant gliomas, the most frequent primary brain tumors, are characterized by a dismal
prognosis. Reliable biomarkers complementary to neuroradiology in the differential …
prognosis. Reliable biomarkers complementary to neuroradiology in the differential …
Potential clinical implications of miR-1 and miR-21 in heart disease and cardioprotection
The interest in non-coding RNAs, which started more than a decade ago, has still not
weakened. A wealth of experimental and clinical studies has suggested the potential of non …
weakened. A wealth of experimental and clinical studies has suggested the potential of non …
Exosomal miR-21 promotes proliferation, invasion and therapy resistance of colon adenocarcinoma cells through its target PDCD4
LH Sun, D Tian, ZC Yang, JL Li - Scientific reports, 2020 - nature.com
Exosomes contain cell-specific collections of bioactive materials including proteins, lipids,
and RNAs that are transported to recipient cells to exert their impacts. MicroRNAs (miRNAs) …
and RNAs that are transported to recipient cells to exert their impacts. MicroRNAs (miRNAs) …
Inflammatory bowel disease biomarkers
Inflammatory bowel disease (IBD) is characterized as chronic inflammation in the
gastrointestinal tract, which includes two main subtypes, Crohn's disease and ulcerative …
gastrointestinal tract, which includes two main subtypes, Crohn's disease and ulcerative …
Synthetic RNA-based logic computation in mammalian cells
S Matsuura, H Ono, S Kawasaki, Y Kuang… - Nature …, 2018 - nature.com
Synthetic biological circuits are designed to regulate gene expressions to control cell
function. To date, these circuits often use DNA-delivery methods, which may lead to random …
function. To date, these circuits often use DNA-delivery methods, which may lead to random …
Exosomal miR-21 regulates the TETs/PTENp1/PTEN pathway to promote hepatocellular carcinoma growth
L Cao, X Yang, Y Chen, D Zhang, XF Jiang, P Xue - Molecular Cancer, 2019 - Springer
Background As an important means of communication, exosomes play an important role in
the development of hepatocellular carcinoma (HCC). Methods Bioinformatics analysis, dual …
the development of hepatocellular carcinoma (HCC). Methods Bioinformatics analysis, dual …