Accurate cancer cell identification and microRNA silencing induced therapy using tailored DNA tetrahedron nanostructures

J Su, F Wu, H Xia, Y Wu, S Liu - Chemical Science, 2020 - pubs.rsc.org
Accurate cancer cell identification and efficient therapy are extremely desirable and
challenging in clinics. Here, we reported the first example of DNA tetrahedron …

Exosomes containing miR-21 transfer the characteristic of cisplatin resistance by targeting PTEN and PDCD4 in oral squamous cell carcinoma

T Liu, G Chen, D Sun, M Lei, Y Li, C Zhou… - Acta biochimica et …, 2017 - academic.oup.com
Resistance to chemotherapy remains a major obstacle for the effective treatment of oral
squamous cell carcinoma (OSCC). Evidence for the involvement of exosomes as important …

Arsenic-induced changes in miRNA expression in cancer and other diseases

APF Cardoso, KT Udoh, JC States - Toxicology and applied pharmacology, 2020 - Elsevier
Abstract miRNAs (miRNA) are essential players regulating gene expression affecting
cellular processes contributing to disease development. Dysregulated miRNA expression …

MicroRNAs in cancer and cardiovascular disease

M Ilieva, R Panella, S Uchida - Cells, 2022 - mdpi.com
Although cardiac tumor formation is rare, accumulating evidence suggests that the two
leading causes of deaths, cancers, and cardiovascular diseases are similar in terms of …

AS1411 aptamer-decorated cisplatin-loaded poly(lactic-co-glycolic acid) Nanoparticles for Targeted Therapy of miR-21-inhibited Ovarian Cancer Cells

S Vandghanooni, M Eskandani, J Barar, Y Omidi - Nanomedicine, 2018 - Taylor & Francis
Aim: The overexpression of miRNA-21 correlates with the cisplatin (CIS) resistance in the
ovarian cancers. Methods: AS1411 antinucleolin aptamer-decorated PEGylated poly (lactic …

The role of microRNA in the development, diagnosis, and treatment of cardiovascular disease: recent developments

A Wronska - Journal of Pharmacology and Experimental …, 2023 - ASPET
Since their discovery in 1993, microRNAs (miRNAs) have emerged as important regulators
of many crucial cellular processes, and their dysregulation have been shown to contribute to …

Apoptosis induced by luteolin in breast cancer: Mechanistic and therapeutic perspectives

S Ahmed, H Khan, D Fratantonio, MM Hasan, S Sharifi… - Phytomedicine, 2019 - Elsevier
Background Breast cancer is worldwide commonly found malignancy in women and
effective treatment is regarded as a huge clinical challenge even in the presence of several …

Identification of modulated MicroRNAs associated with breast cancer, diet, and physical activity

L Falzone, M Grimaldi, E Celentano, LSA Augustin… - Cancers, 2020 - mdpi.com
Simple Summary Healthy diet and physical activity are able to induce beneficial molecular
modifications that have been associated with a lower risk of breast cancer (BC) incidence …

[HTML][HTML] MicroRNAs as clinical tools for diagnosis, prognosis, and therapy in prostate cancer

F Ghamlouche, A Yehya, Y Zeid, H Fakhereddine… - Translational …, 2023 - Elsevier
Prostate cancer (PCa) is one of the most commonly diagnosed cancers among men
worldwide. Despite the presence of accumulated clinical strategies for PCa management …

Breast cancer-delivered exosomal miRNA as liquid biopsy biomarkers for metastasis prediction: a focus on translational research with clinical applicability

O Baldasici, V Pileczki, D Cruceriu, LI Gavrilas… - International Journal of …, 2022 - mdpi.com
Metastasis represents the most important cause of breast cancer-associated mortality. Even
for early diagnosed stages, the risk of metastasis is significantly high and predicts a grim …