Glutamate-mediated excitotoxicity is an important mechanism leading to post ischemic
stroke damage. After acute stroke, the sudden reduction in cerebral blood flow is most …

Abstract Oligodendrocytes (OLs), the myelin-forming cells of the central nervous system, are
integral to axonal integrity and function. Hypoxia-ischemia episodes can cause severe …

In the central nervous system (CNS), the myelin sheath ensures efficient interconnection
between neurons and contributes to the regulation of the proper function of neuronal …

P2X receptors belong to a family of cation channel proteins, which respond to extracellular
adenosine 5′-triphosphate (ATP). These receptors have gained increasing attention in …

The development of cerebral ischemia involves brain damage and abnormal changes in
brain function, which can cause neurosensory and motor dysfunction, and bring serious …

P2X7, an ion channel gated by extracellular ATP, is widely expressed on the plasma
membrane of immune cells and plays important roles in inflammation and apoptosis …

Role of the purinergic signaling network in lung ischemia-re... : Current Opinion in Organ
Transplantation Role of the purinergic signaling network in lung ischemia-reperfusion injury …

As a kind of environmental noise, infrasonic noise has negative effects on various human
organs. To date, research has shown that infrasound impairs cognitive function, especially …

The purinergic system is defined as a universal regulatory system allowing individual
cellular responses to be calibrated and synchronized such that they correspond to the …

ABSTRACT Pannexin-1 (Panx1) is a large-pore ion and metabolite channel with broad
cell/tissue expression, including neurons and glia of the central nervous system. Panx1 is …