Implications of glial nitric oxide in neurodegenerative diseases

JE Yuste, E Tarragon, CM Campuzano… - Frontiers in cellular …, 2015 - frontiersin.org
Nitric oxide (NO) is a pleiotropic janus-faced molecule synthesized by nitric oxide synthases
(NOS) which plays a critical role in a number of physiological and pathological processes in …

Nitric oxide and peroxynitrite in health and disease

P Pacher, JS Beckman, L Liaudet - Physiological reviews, 2007 - journals.physiology.org
The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Nitric oxide synthases: structure, function and inhibition

WK Alderton, CE Cooper, RG Knowles - Biochemical journal, 2001 - portlandpress.com
This review concentrates on advances in nitric oxide synthase (NOS) structure, function and
inhibition made in the last seven years, during which time substantial advances have been …

The physiology and pathophysiology of nitric oxide in the brain

FX Guix, I Uribesalgo, M Coma, FJ Munoz - Progress in neurobiology, 2005 - Elsevier
Nitric oxide (NO) is a molecule with pleiotropic effects in different tissues. NO is synthesized
by NO synthases (NOS), a family with four major types: endothelial, neuronal, inducible and …

Environmental-induced oxidative stress in neurodegenerative disorders and aging

L Migliore, F Coppedè - Mutation Research/Genetic Toxicology and …, 2009 - Elsevier
The aetiology of most neurodegenerative disorders is multifactorial and consists of an
interaction between environmental factors and genetic predisposition. Free radicals derived …

Arginine metabolism and the synthesis of nitric oxide in the nervous system

H Wiesinger - Progress in neurobiology, 2001 - Elsevier
The biochemistry and physiology of l-arginine have to be reconsidered in the light of the
recent discovery that the amino acid is the only substrate of all isoforms of nitric oxide …

Immunoexcitotoxicity as a Central Mechanism of Chronic Traumatic Encephalopathy–A Unifying Hypothesis

RL Blaylock, MD Maroon, C Joseph - 2012 - books.rsc.org
Approximately 1.7 million people in the United States annually experience a traumatic brain
injury (TBI). 1 The number of unreported head injuries is much higher. Sports-related head …

Say NO to Alzheimer's disease: the putative links between nitric oxide and dementia of the Alzheimer's type

A Law, S Gauthier, R Quirion - Brain research reviews, 2001 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia, with progressive cognitive
deficits being the primary symptom. AD is neuropathologically characterized by amyloid and …

Preventive Effect of Limosilactobacillus fermentum SCHY34 on Lead Acetate-Induced Neurological Damage in SD Rats

X Long, H Wu, Y Zhou, Y Wan, X Kan, J Gong… - Frontiers in …, 2022 - frontiersin.org
Lead poisoning caused by lead pollution seriously affects people's health. Lactic acid
bacteria has been shown to be useful for biological scavenging of lead. In this experiment …

Nitric oxide and nitroxidative stress in Alzheimer's disease

T Malinski - Journal of Alzheimer's disease, 2007 - content.iospress.com
Nitric oxide is a signaling molecule produced by neurons and endothelial cells in the brain.
NO is synthesized from L-arginine and oxygen by nitric oxide synthase: neuronal (nNOS) …