Alzheimer's disease (AD) is a disorder that causes degeneration of the cells in the brain and
it is the main cause of dementia, which is characterized by a decline in thinking and …

Nutrition is an important lifestyle factor that can modify the risk of future cognitive impairment
and dementia. Some, but not conclusive, evidence (mostly from observational studies and …

Patients with chronic kidney disease (CKD) are at substantially higher risk for developing
cognitive impairment compared with the general population, and both lower glomerular …

Cerebral blood flow (CBF) reductions in Alzheimer's disease patients and related mouse
models have been recognized for decades, but the underlying mechanisms and resulting …

Although there is no unanimity, growing evidence supports the value of regular physical
exercise to prevent Alzheimer's disease as well as cognitive decline in affected patients …

Objectives: Identify the risk factors associated with Alzheimer disease. Describe the atypical
presentations of Alzheimer disease. Summarize and differentiate between the preclinical …

The symptoms of Alzheimer disease reflect a loss of neural circuit integrity in the brain, but
neurons do not work in isolation. Emerging evidence suggests that the intricate balance of …

Vascular contributions to cognitive impairment and dementia (VCID) are characterized by
the aging neurovascular unit being confronted with and failing to cope with biological insults …

Alzheimer's disease (AD) is the most common cause of dementia and is characterized by
progressive neurodegeneration and cognitive decline. Understanding the pathophysiology …

Brain capillary endothelial cells form the blood-brain barrier (BBB), which is covered with
basement membranes and is also surrounded by pericytes and astrocyte end-feet in the …