Abstract Next-generation sequencing (NGS), also known as massively parallel sequencing,
has revolutionized genomic research. The current advances in NGS technology make it …

The ongoing or anticipated therapeutic advances as well as previous experience in other
malignancies, including acute myeloid leukaemia, have made molecular monitoring a …

Given limited studies on next-generation sequencing-based measurable residual disease
(NGS-MRD) in acute myeloid leukemia (AML) patients after allogeneic hematopoietic stem …

Chimerism analysis is a well-established method for monitoring the state of hematopoietic
stem cell transplantation (HSCT) over time by analyzing peripheral blood or bone marrow …

Background Quantification of chimerism showing the proportion of the donor in a recipient is
essential for the follow-up of hematopoietic stem cell transplantation but can also be useful …

This study aimed to validate the new European Leukemia Net (ELN) 2022 criteria for genetic
risk stratification in older adults with acute myeloid leukemia (AML) and to determine the …

Background/aims Chimerism monitoring by means of high-throughput sequencing or
quantitative PCR of biallelic single nucleotide and insertion/deletion polymorphisms has …

Chimerism monitoring after allogenic Hematopoietic Cell Transplantation (allo-HCT) is
critical to determine how well donor cells have engrafted and to detect relapse for early …

HLA loss in hematologic malignancies is rare at diagnosis but may occur in leukemic cells at
disease relapse. Although HLA mismatched hematopoietic cell transplant (HCT) is useful in …

Simple Summary The final stages of myeloproliferative neoplasms (MPNs) are related to
myelofibrosis (MF). This study aimed to compare secondary myelofibrosis (SMF), overt …