Risks and risk management in modern multiple sclerosis immunotherapeutic treatment

L Klotz, J Havla, N Schwab, R Hohlfeld… - Therapeutic …, 2019 - journals.sagepub.com
In recent years, there has been a paradigm shift in the treatment of multiple sclerosis (MS)
owing to the approval of a number of new drugs with very distinct mechanisms of action. All …

How B cells shape the immune response against Mycobacterium tuberculosis

PJ Maglione, J Chan - European journal of immunology, 2009 - Wiley Online Library
Extensive work illustrating the importance of cellular immune mechanisms for protection
against Mycobacterium tuberculosis has largely relegated B‐cell biology to an afterthought …

Progressive enhancement of kinetic proofreading in T cell antigen discrimination from receptor activation to DAG generation

DM Britain, JP Town, OD Weiner - Elife, 2022 - elifesciences.org
T cells use kinetic proofreading to discriminate antigens by converting small changes in
antigen-binding lifetime into large differences in cell activation, but where in the signaling …

Alcohol consumption in rheumatoid arthritis: a path through the immune system

V Azizov, MM Zaiss - Nutrients, 2021 - mdpi.com
Benefits and harms of different components of human diet have been known for hundreds of
years. Alcohol is one the highest consumed, abused, and addictive substances worldwide …

Pattern formation and transition to chaos in a chemotaxis model of acute inflammation

V Giunta, MC Lombardo, M Sammartino - SIAM Journal on Applied Dynamical …, 2021 - SIAM
We investigate a reaction-diffusion-chemotaxis system that describes the immune response
during an inflammatory attack. The model is a modification of the system proposed in …

[HTML][HTML] Korean Red Ginseng affects ovalbumin-induced asthma by modulating IL-12, IL-4, and IL-6 levels and the NF-κB/COX-2 and PGE2 pathways

SY Lee, MH Kim, SH Kim, T Ahn, SW Kim… - Journal of Ginseng …, 2021 - Elsevier
Background Asthma is an incurable hyper-responsive disease of the pulmonary system that
is caused by various allergens, including indoor and outdoor stimulators. According to the …

Contribution to herpesvirus surveillance in beaked whales stranded in the Canary Islands

I Felipe-Jiménez, A Fernández, M Andrada, M Arbelo… - Animals, 2021 - mdpi.com
Simple Summary Herpesviruses (HVs) are a large family of DNA viruses infecting animals
(including insects and mollusks) and humans. Cetaceans can be also infected by HVs …

Acute and sub-acute toxicity profile of crude extract and fractions of Gymnema sylvestre

RO Raji, HL Muhammad, A Abubakar, SS Maikai… - Clinical …, 2021 - Springer
Background Gymnema sylvestre is a reputable medicinal plant commonly explore for the
management of diabetes and other ailments in traditional medicine. In the present study, we …

An mRNA-based platform for the delivery of pathogen-specific IgA into mucosal secretions

CE Deal, AF Richards, T Yeung, MJ Maron, Z Wang… - Cell Reports …, 2023 - cell.com
Colonization of the gut and airways by pathogenic bacteria can lead to local tissue
destruction and life-threatening systemic infections, especially in immunologically …

[PDF][PDF] Immunosuppressants: A review

P Rathee, H Chaudhary, S Rathee, D Rathee… - The Pharma …, 2013 - academia.edu
Advances in immunosuppressants over the past decade have resulted in dramatic
improvements in short-and long-term outcomes in organ transplantation as well as a …