Oral squamous cell carcinomas: state of the field and emerging directions

Y Tan, Z Wang, M Xu, B Li, Z Huang, S Qin… - International journal of …, 2023 - nature.com
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …

Cuproptosis: Harnessing transition metal for cancer therapy

W Wang, W Mo, Z Hang, Y Huang, H Yi, Z Sun, A Lei - ACS nano, 2023 - ACS Publications
Transition metal elements, such as copper, play diverse and pivotal roles in oncology. They
act as constituents of metalloenzymes involved in cellular metabolism, function as signaling …

[HTML][HTML] Drug-induced oxidative stress in cancer treatments: Angel or devil?

H Jiang, J Zuo, B Li, R Chen, K Luo, X Xiang, S Lu… - Redox Biology, 2023 - Elsevier
Oxidative stress (OS), defined as redox imbalance in favor of oxidant burden, is one of the
most significant biological events in cancer progression. Cancer cells generally represent a …

Managing the immune microenvironment of osteosarcoma: the outlook for osteosarcoma treatment

H Tian, J Cao, B Li, EC Nice, H Mao, Y Zhang… - Bone Research, 2023 - nature.com
Osteosarcoma, with poor survival after metastasis, is considered the most common primary
bone cancer in adolescents. Notwithstanding the efforts of researchers, its five-year survival …

Nanotechnology-empowered strategies in treatment of skin cancer

J Chandra, N Hasan, N Nasir, S Wahab… - Environmental …, 2023 - Elsevier
In current scenario skin cancer is a serious condition that has a significant impact on world
health. Skin cancer is divided into two categories: melanoma skin cancer (MSC) and non …

Brain‐targeted HFn‐Cu‐rego nanoplatform for site‐specific delivery and manipulation of autophagy and cuproptosis in glioblastoma

W Jia, H Tian, J Jiang, L Zhou, L Li, M Luo, N Ding… - Small, 2023 - Wiley Online Library
Durable glioblastoma multiforme (GBM) management requires long‐term chemotherapy
after surgery to eliminate remaining cancerous tissues. Among chemotherapeutics …

Targeting glucose metabolism enzymes in cancer treatment: current and emerging strategies

Y Zhang, Q Li, Z Huang, B Li, EC Nice, C Huang, L Wei… - Cancers, 2022 - mdpi.com
Simple Summary Reprogramming of glucose metabolism is a hallmark of cancer and can be
targeted by therapeutic agents. Some metabolism regulators, such as ivosidenib and …

Targeting toll-like receptor 7/8 for immunotherapy: recent advances and prospectives

H Sun, Y Li, P Zhang, H Xing, S Zhao, Y Song… - Biomarker …, 2022 - Springer
Toll-like receptors (TLRs) are a large family of proteins that are expressed in immune cells
and various tumor cells. TLR7/8 are located in the intracellular endosomes, participate in …

[HTML][HTML] Doxorubicin-loaded Niosomes functionalized with gelatine and alginate as pH-responsive drug delivery system: A 3D printing approach

M Zaer, A Moeinzadeh, H Abolhassani… - International Journal of …, 2023 - Elsevier
Despite many efforts, breast cancer remains one of the deadliest cancers and its treatment
faces challenges related to cancer drug side effects and metastasis. Combining 3D printing …

Molecularly imprinted polymers (MIPs): emerging biomaterials for cancer theragnostic applications

MS Kang, E Cho, HE Choi, C Amri, JH Lee… - Biomaterials …, 2023 - spj.science.org
Cancer is a disease caused by abnormal cell growth that spreads through other parts of the
body and threatens life by destroying healthy tissues. Therefore, numerous techniques have …