Patients with hypertensive emergencies, malignant hypertension and acute severe
hypertension are managed heterogeneously in clinical practice. Initiating anti-hypertensive …

Background Acute heart failure is a public health concern. This study systematically
reviewed randomized clinical trials (RCTs) to evaluate vasodilators in acute heart failure …

Aims Currently, no acute heart failure (AHF) therapy definitively improves outcomes.
Reducing morbidity and mortality from acute heart failure (AHF) remains an unmet need …

A hypertensive emergency is a clinical diagnosis that is appropriate when marked
hypertension is associated with acute target-organ damage; in this setting, lowering of blood …

Abstract The BLAST-AHF (Biased Ligand of the Angiotensin Receptor Study in Acute Heart
Failure) study is designed to test the efficacy and safety of TRV027, a novel biased ligand of …

Hypertensive emergencies occur when high blood pressure is associated with the presence
of acute end-organ damage, such as hypertensive encephalopathy. There is controversy as …

Acute heart failure syndromes (AHFS) are a major public health problem and present a
therapeutic challenge to clinicians. Commonly used agents in the treatment of AHFS include …

There are nearly 700,000 annual US emergency department (ED) visits for acute heart
failure (AHF). Although blood pressure is elevated on most of these visits, acute therapy …

Current medical treatment for the exacerbation of chronic heart failure resulting in hospitalization
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Cardiogenic pulmonary edema (CPE) is a common and potentially deadly condition
frequently encountered in emergency medicine. Many conditions exist that directly or …