[HTML][HTML] NSD1 mutations by HPV status in head and neck cancer: differences in survival and response to DNA-damaging agents
C Pan, S Izreig, WG Yarbrough, N Issaeva - Cancers of the Head & Neck, 2019 - Springer
Background Compared to HPV-negative head and neck squamous cell carcinomas
(HNSCCs), HPV-positive HNSCCs are associated with a favorable prognosis in part due to …
(HNSCCs), HPV-positive HNSCCs are associated with a favorable prognosis in part due to …
[HTML][HTML] Low expression of NSD1, NSD2, and NSD3 define a subset of human papillomavirus-positive oral squamous carcinomas with unfavorable prognosis
Background Frequent mutations in the nuclear receptor binding SET domain protein 1
(NSD1) gene have been observed in head and neck squamous cell carcinomas (HNSCC) …
(NSD1) gene have been observed in head and neck squamous cell carcinomas (HNSCC) …
[HTML][HTML] Analysis of the TCGA dataset reveals that subsites of laryngeal squamous cell carcinoma are molecularly distinct
Simple Summary Squamous cell carcinomas from different parts of the larynx have distinct
presentations and prognoses, but the molecular basis for this discrepancy has yet to be …
presentations and prognoses, but the molecular basis for this discrepancy has yet to be …
Tumor molecular differences associated with outcome disparities of Black patients with head and neck cancer
Background Numerous studies of head and neck squamous cell carcinoma (HNSCC) have
demonstrated disparate outcomes by race and ethnicity. Beyond known associations with …
demonstrated disparate outcomes by race and ethnicity. Beyond known associations with …
HPV‐negative head and neck cancers with adverse pathological features carry specific molecular changes that are associated with survival
Background Adverse pathological features following surgery in head and neck squamous
cell carcinoma (HNSCC) are strongly associated with survival and guide adjuvant therapy …
cell carcinoma (HNSCC) are strongly associated with survival and guide adjuvant therapy …
[HTML][HTML] 3p arm loss and survival in head and neck cancer: an analysis of TCGA dataset
Simple Summary Loss of the 3p chromosome arm has previously been reported to be a
predictor of poorer outcome in head and neck cancer regardless of human papillomavirus …
predictor of poorer outcome in head and neck cancer regardless of human papillomavirus …
[HTML][HTML] Immunogenomic alterations of head and neck squamous cell carcinomas stratified by smoking status
Y Huang, P Zhang - Clinical and Translational Medicine, 2021 - ncbi.nlm.nih.gov
Dear Editor, Accumulating evidence revealed that the immunologic sequelae of smoking
may contribute to the progression and treatment resistance of various cancer types …
may contribute to the progression and treatment resistance of various cancer types …
The importance of smoking status at diagnosis in human papillomavirus‐associated oropharyngeal cancer
HY Liu, CP Daniels, Y Trada, A Bernard, KH You… - Head & …, 2021 - Wiley Online Library
Background Smoking status at point of diagnosis is not used in defining risk groups for
human papillomavirus (HPV)‐associated oropharyngeal cancer (OPC) despite its prognostic …
human papillomavirus (HPV)‐associated oropharyngeal cancer (OPC) despite its prognostic …
Spleen tyrosine kinase expression is correlated with human papillomavirus in head and neck cancer
M Black, F Ghasemi, RX Sun, W Stecho, A Datti… - Oral Oncology, 2020 - Elsevier
Objectives Spleen tyrosine kinase (SYK) is a promoter of cell survival in a variety of cell
types, including normal and cancerous epithelial cells. We hypothesized that SYK would an …
types, including normal and cancerous epithelial cells. We hypothesized that SYK would an …
Subclass-specific prognosis and treatment efficacy inference in head and neck squamous carcinoma
Exploring the prognostic classification and biomarkers in Head and Neck Squamous
Carcinoma (HNSC) is of great clinical significance. We hybridized three prominent strategies …
Carcinoma (HNSC) is of great clinical significance. We hybridized three prominent strategies …