Mechanisms of action of current pharmacologic options for the treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation

GS Sayuk, SA Waldman… - Official journal of the …, 2022 - journals.lww.com
Multiple therapeutic agents are currently available for the treatment of chronic idiopathic
constipation and irritable bowel syndrome with constipation. A better understanding of the …

Effects of cannabidiol chewing gum on perceived pain and well-being of irritable bowel syndrome patients: a placebo-controlled crossover exploratory intervention …

ACB van Orten-Luiten, NM De Roos… - Cannabis and …, 2022 - liebertpub.com
Background: Irritable bowel syndrome (IBS) is one of the most common gastrointestinal
disorders. Its pathophysiology is diverse and variable, involving disturbed gut–brain …

current and future treatment approaches for IBS with constipation

JJ Liu, DM Brenner - Alimentary Pharmacology & Therapeutics, 2021 - Wiley Online Library
Background Multiple efficacious therapies are currently available for treating irritable bowel
syndrome with constipation (IBS‐C). IBS‐C specific survey tools that assess symptom relief …

Application of plant secondary metabolites to pain neuromodulation

RK Singla, AG Guimarães, G Zengin - Frontiers in Pharmacology, 2021 - frontiersin.org
Pain is a highly unpleasant and intolerable condition, which is associated with multiple
diseases and disorders, including but not limited to cancer, diabetes, infectious diseases …

Cannabinoid receptors overexpression in a rat model of irritable bowel syndrome (IBS) after treatment with a ketogenic diet

I Gigante, V Tutino, F Russo, V De Nunzio… - International Journal of …, 2021 - mdpi.com
The administration of a ketogenic diet (KD) has been considered therapeutic in subjects with
irritable bowel syndrome (IBS). This study aimed to investigate the molecular mechanisms …

Neuro-Gastro-Cannabinology: A Novel Paradigm for Regulating Mood and Digestive Health

F Turco, V Brugnatelli, R Abalo - Medical Cannabis and Cannabinoids, 2023 - karger.com
The maintenance of homeostasis in the gastrointestinal (GI) tract is ensured by the presence
of the endocannabinoid system (ECS), which regulates important physiological activities …

Why use nutraceutical strategies for the irritable bowel syndrome?

F di Michele - Current Medicinal Chemistry, 2022 - ingentaconnect.com
Irritable bowel syndrome (IBS) is a chronic functional bowel disorder, often stress-related,
identified by many abdominal symptoms, the most important of which is chronic visceral …

Neuro-Gastro-Cannabinology: A Novel Paradigm for Regulating Mood and Digestive Health

FTVBR Abalob - 2023 - karger.com
The maintenance of homeostasis in the gastrointestinal (GI) tract is ensured by the presence
of the endocannabinoid system (ECS), which regulates important physiological activities …

[PDF][PDF] Thope Moqejwa

YE Choonara - 2022 - wiredspace.wits.ac.za
Cannabidiol is a non-psychoactive compound of cannabis that has been demonstrated to
alleviate pain and inflammation. However, its clinical application is hampered by …

[HTML][HTML] CBD for IBS: What the Latest Research Says

JHU June, A a Budtender - nuggmd.com
IBS is one of the most common conditions doctors treat in their offices. Treatments for IBS
focus on individual symptoms, but no single remedy covers all of its symptoms. According to …