Abstract Coronavirus disease 2019 (COVID‐19) is an acute respiratory infectious disease
caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). COVID‐19 …

Type 2 diabetes mellitus (T2DM) leads to many health problems like diabetic nephropathy
(DN). One of the key factors for chronic kidney disease and end-stage renal disease (ESRD) …

Rationale: Ischemia/reperfusion injury (IRI) is a major cause of acute kidney injury (AKI) that
is associated with high morbidity and mortality, and for which specific treatments are lacking …

Chronic kidney disease (CKD) will become the fifth global cause of death by 2040, thus
emphasizing the need to better understand the molecular mechanisms of damage and …

Coronavirus disease 2019 (COVID-19) continues to burden society worldwide. Despite most
patients having a mild course, severe presentations have limited treatment options. COVID …

Renal failure has a high prevalence and is becoming a public health problem worldwide.
However, the renal replacement therapies such as dialysis are not yet satisfactory for its …

Background Hepatocyte NF 4α (Hnf4a) is a major regulator of renal proximal tubule (PT)
development. In humans, a mutation in HNF4A impairs PT functions and is associated with …

Limitations in the current therapeutic strategies for the prevention of progression of chronic
kidney disease (CKD) to end stage renal disease has been a drawback to improving patient …

Kidney disease (KD) is a life-threatening disease characterized by high morbidity and
mortality in clinical settings, which can be caused by many reasons, and the incidence …

Ischemia-reperfusion injury (IRI) plays a significant role in the pathogenesis of acute kidney
injury (AKI). The complicated interaction between injured tubular cells, activated endothelial …