Characterization of the genomic alterations in poorly differentiated thyroid cancer

Y Lee, SR Moon, JY Seok, JH Lee, S Nam… - Scientific Reports, 2023 - nature.com
Poorly differentiated thyroid carcinoma (PDTC) is a subtype of thyroid cancer that has a high
rate of metastasis or recurrence and a relatively poor prognosis. However, there are few …

Management of Poorly Differentiated Thyroid Cancer and Differentiated High-Grade Thyroid Carcinoma

IS Alam, KN Patel - Surgical Clinics, 2024 - surgical.theclinics.com
Thyroid carcinoma of follicular cell origin exists on a histopathologic and clinical spectrum.
On one end, up to 87% of thyroid cancers are well-differentiated and have a very favorable …

Poorly differentiated thyroid carcinomas: conceptual controversy and clinical impact

A Coca-Pelaz, JP Rodrigo, A Agaimy, MD Williams… - Virchows Archiv, 2024 - Springer
Poorly differentiated thyroid carcinomas (PDTC) are rare diseases; nevertheless, they
account for the majority of deaths from non-anaplastic follicular cell-derived thyroid …

Expression of pY397-FAK and Its miR Regulators Drive Dedifferentiation in the Thyroid Neoplasia Spectrum

V Ignjatović Jocić, J Janković Miljuš, T Išić Denčić… - Cells, 2023 - mdpi.com
Thyroid carcinomas are growing malignancies worldwide. They encompass several
diagnostic categories with varying degrees of dedifferentiation. Focal adhesion kinase is …

Revisiting the cytomorphological features of poorly differentiated thyroid carcinoma: A comparative analysis with indeterminate thyroid fine-needle aspiration samples

Y Alwelaie, A Howaidi, M Tashkandi, A Almotairi… - Journal of the American …, 2023 - Elsevier
Introduction Poorly differentiated thyroid carcinoma (PDTC) is an uncommon high-grade
carcinoma of follicular cell origin that is usually overlooked on preoperative fine-needle …

Outcomes of lenvatinib therapy in poorly differentiated thyroid carcinoma

J Roque, TN Silva, C Regala… - European Thyroid …, 2023 - etj.bioscientifica.com
Background and objective Lenvatinib showed promising results in a subgroup of patients
with poorly differentiated thyroid carcinoma (PDTC) in the SELECT trial. Our aim was to …

A Misleading Case of NTRK-Rearranged Papillary Thyroid Carcinoma

MM Germani, C Boccaccio, A Matrone… - The …, 2024 - academic.oup.com
Herein, we present a misleading case of advanced papillary thyroid carcinoma with lung,
node, and pleural metastases, initially diagnosed as metastatic lung adenocarcinoma with …

A Comprehensive Review and Insights into the New Entity of Differentiated High-Grade Thyroid Carcinoma

AS Harahap, RS Roren, S Imtiyaz - Current Oncology, 2024 - mdpi.com
Differentiated high-grade thyroid carcinoma (DHGTC) is a new subset within the spectrum of
thyroid malignancies. This review aims to provide a comprehensive overview of DHGTC …

Cut-off Value for Thyroglobulin Washout Concentration in the Detection of Cervical Lymph Node Metastases in Patients after Thyroidectomy Due to Differentiated …

P Mikosiński, E Wołowiec-Korecka, L Pomorski… - Biomedicines, 2023 - mdpi.com
The aim of this study was to establish the cut-off value for the thyroglobulin (Tg)
concentration in washout fluid from fine needle aspiration biopsy (FNA-Tg) in the detection …

Diagnosis and Treatment of Acute Pleural Effusion following Radioiodine Remnant Ablation Post Lobectomy for Thyroid Cancer

X Qiu, P Wang, R Sa, L Cheng, Y Jin, H Song, L Chen - Diagnostics, 2022 - mdpi.com
Radioiodine remnant ablation (RRA) was previously demonstrated to be a safe and effective
alternative to completion thyroidectomy for patients with differentiated thyroid cancer (DTC) …