Medicinal plants have historically proven their value as a source of molecules with
therapeutic potential, and nowadays still represent an important pool for the identification of …

The unprecedented use of antibiotics that led to development of resistance affect human
health worldwide. Prescription of antibiotics imprudently and irrationally in different diseases …

Organ-on-a-chip devices have enabled major breakthroughs in biomedical research, but
they have yet to be successfully translated to the pharmaceutical industry. Traditional …

Broad‐spectrum antibiotics target multiple gram‐positive and gram‐negative bacteria, and
can collaterally damage the gut microbiota. Yet, our knowledge of the extent of damage, the …

Therapeutic drug development is a long, expensive, and complex process that usually takes
12–15 years. In the early phases of drug discovery, in particular, there is a growing need for …

Marine natural products represent novel and diverse chemotypes that serve as templates for
the discovery and development of therapeutic agents with distinct mechanisms of action …

In the forms of either herbs or functional foods, plants and their products have attracted
medicinal, culinary, and nutraceutical applications due to their abundance in bioactive …

There is a well-defined regulatory framework governing the approval of chemicals for use as
pharmaceuticals or release into the environment. Toxicity assessment is thus a major hurdle …

Abstract Di-(2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer with a high
environmental exposure level. As a persistent organic pollutant, DEHP causes reproductive …

ROS (reactive oxygen species) are potentially damaging by-products of aerobic metabolism
which, unchecked, can have detrimental effects on cell function. However, it is now widely …