Secondary stroke prevention

GJ Hankey - The Lancet Neurology, 2014 - thelancet.com
Survivors of stroke and transient ischaemic attacks are at risk of a recurrent stroke, which is
often more severe and disabling than the index event. Optimum secondary prevention of …

Anticoagulant effects of statins and their clinical implications

A Undas, KE Brummel-Ziedins… - Thrombosis and …, 2014 - thieme-connect.com
There is evidence indicating that statins (3-hydroxy-methylglutaryl coenzyme A reductase
inhibitors) may produce several cholesterol-independent antithrombotic effects. In this …

Early high-dose rosuvastatin for contrast-induced nephropathy prevention in acute coronary syndrome: Results from the PRATO-ACS Study (Protective Effect of …

M Leoncini, A Toso, M Maioli, F Tropeano… - Journal of the American …, 2014 - jacc.org
Objectives: This study sought to determine if in addition to standard preventive measures on-
admission, high-dose rosuvastatin exerts a protective effect against contrast-induced acute …

[HTML][HTML] Behavioral nudges as patient decision support for medication adherence: the ENCOURAGE randomized controlled trial

BD Horne, JB Muhlestein, DL Lappé, HT May… - American Heart …, 2022 - Elsevier
Background Medication adherence is generally low and challenging to address because
patient actions control healthcare delivery outside of medical environments. Behavioral …

Comparison of lipid-modifying efficacy of rosuvastatin versus atorvastatin in patients with acute coronary syndrome (from the LUNAR study)

B Pitt, J Loscalzo, J Monyak, E Miller… - The American journal of …, 2012 - Elsevier
Patients with acute coronary syndrome are recommended for early aggressive low-density
lipoprotein (LDL) cholesterol–lowering therapy. The LUNAR study compared the efficacy of …

Statins for acute coronary syndrome

N Vale, AJ Nordmann, GG Schwartz… - Cochrane Database …, 2014 - cochranelibrary.com
Background The early period following the onset of acute coronary syndrome (ACS)
represents a critical stage of coronary heart disease, with a high risk of recurrent events and …

Predictors of LDL-cholesterol target value attainment differ in acute and chronic coronary heart disease patients: results from DYSIS II Europe

J Ferrieres, GM De Ferrari, MP Hermans… - European journal of …, 2018 - academic.oup.com
Background Patients with coronary heart disease (CHD) and survivors of acute coronary
syndrome (ACS) are at very high risk for adverse cardiovascular events. Lowering low …

Comparison of atorvastatin 80 mg/day versus simvastatin 20 to 40 mg/day on frequency of cardiovascular events late (five years) after acute myocardial infarction …

TR Pedersen, NB Cater, O Faergeman… - The American journal of …, 2010 - Elsevier
Previous studies have demonstrated that benefits of intensive statin therapy compared to
standard statin therapy begin shortly after an acute event and are continued up to 2 years of …

Timing and dose of statin therapy define its impact on inflammatory and endothelial responses during myocardial infarction

AC Sposito, SN Santos, EC de Faria… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—Clinical trials of statins during myocardial infarction (MI) have differed in their
therapeutic regimes and generated conflicting results. This study evaluated the role of the …

Update on the efficacy of statin treatment in acute coronary syndromes

GM Rosa, F Carbone, A Parodi… - European journal of …, 2014 - Wiley Online Library
Background The natural history of atherosclerosis might involve coronary plaque
rupture/erosion, thrombus formation and vessel lumen occlusion, clinically recognized as …