Esculeoside A decreases diabetic cardiomyopathy in streptozotocin-treated rats by attenuating oxidative stress, inflammation, fibrosis, and apoptosis: impressive role …

JZ ALTamimi, NA AlFaris, GM Alshammari, RI Alagal… - Medicina, 2023 - mdpi.com
Background and Objectives: This experiment evaluated the preventative influence of the
tomato-derived Esculeoside A (ESA) on diabetic cardiomyopathy in type 1 diabetes mellitus …

[HTML][HTML] Diabetes and cognitive function: An evidence-based current perspective

MJ Sebastian, SKA Khan, JM Pappachan… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Several epidemiological studies have clearly identified diabetes mellitus (DM) as a major
risk factor for cognitive dysfunction, and it is going to be a major public health issue in the …

Insight into continuous glucose monitoring: from medical basics to commercialized devices

A Chmayssem, M Nadolska, E Tubbs, K Sadowska… - Microchimica Acta, 2023 - Springer
According to the latest statistics, more than 537 million people around the world struggle
with diabetes and its adverse consequences. As well as acute risks of hypo-or hyper …

Umbilical cord-derived mesenchymal stromal cells preserve endogenous insulin production in type 1 diabetes: a phase I/II randomised double-blind placebo …

PO Carlsson, D Espes, S Sisay, LC Davies, CIE Smith… - Diabetologia, 2023 - Springer
Aim/hypothesis This study aimed to investigate the safety and efficacy of treatment with
allogeneic Wharton's jelly-derived mesenchymal stromal cells (MSCs) in recent-onset type 1 …

Changes in the global epidemiology of type 1 diabetes in an evolving landscape of environmental factors: causes, challenges, and opportunities

I Ogrotis, T Koufakis, K Kotsa - Medicina, 2023 - mdpi.com
The worldwide incidence of type 1 diabetes mellitus (T1DM) has increased in recent
decades. The reasons behind this phenomenon are not yet fully understood. Early life …

Incretins beyond type 2 diabetes

C Mathieu, I Ahmadzai - Diabetologia, 2023 - Springer
Incretin-based therapies, in particular glucagon-like peptide-1 (GLP-1) receptor agonists,
have been evaluated in other forms of diabetes, but randomised controlled trials are mainly …

TYK2 signaling promotes the development of autoreactive CD8+ cytotoxic T lymphocytes and type 1 diabetes

K Mine, S Nagafuchi, S Akazawa, N Abiru… - Nature …, 2024 - nature.com
Abstract Tyrosine kinase 2 (TYK2), a member of the JAK family, has attracted attention as a
potential therapeutic target for autoimmune diseases. However, the role of TYK2 in CD8+ T …

N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine

F Ma, H Li, H Huo, Q Han, J Liao, H Zhang, Y Li, J Pan… - Life Sciences, 2023 - Elsevier
Diabetic nephropathy (DN) is a major complication of type 1 diabetes mellitus, and
hyperglycemia and hypertension are the main risk factors for the development of DN. N …

The Current Status of Allogenic Islet Cell Transplantation

Z Czarnecka, N Dadheech, H Razavy, R Pawlick… - Cells, 2023 - mdpi.com
Type 1 Diabetes (T1D) is an autoimmune destruction of pancreatic beta cells. The
development of the Edmonton Protocol for islet transplantation in 2000 revolutionized T1D …

Autoimmune liver diseases and diabetes: a propensity score matched analysis and a proportional meta‐analysis

ASH Jensen, M Winther‐Sørensen, J Burisch… - Liver …, 2023 - Wiley Online Library
Abstract Background and Aims Patients with some chronic liver diseases have increased
risk of diabetes. Whether this is also the case for patients with autoimmune liver diseases is …