Islet cells in human type 1 diabetes: from recent advances to novel therapies–a symposium-based roadmap for future research
J Cantley, DL Eizirik, E Latres… - Journal of …, 2023 - joe.bioscientifica.com
There is a growing understanding that the early phases of type 1 diabetes (T1D) are
characterised by a deleterious dialogue between the pancreatic beta cells and the immune …
characterised by a deleterious dialogue between the pancreatic beta cells and the immune …
Fatty acid-mediated signaling as a target for developing type 1 diabetes therapies
I Díaz Ludovico, S Sarkar, E Elliott… - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction Type 1 diabetes (T1D) is an autoimmune disease in which pro-
inflammatory and cytotoxic signaling drive the death of the insulin-producing β cells. This …
inflammatory and cytotoxic signaling drive the death of the insulin-producing β cells. This …
Influence of family social support and diabetes self-efficacy on the emotional wellbeing of children and adolescents with type 1 diabetes: A longitudinal study
Type 1 diabetes (T1D) is a chronic disease that is usually diagnosed in childhood,
underscoring the importance of early disease control for overall wellbeing. Our aim was to …
underscoring the importance of early disease control for overall wellbeing. Our aim was to …
The T1D index: implications of initial results, data limitations, and future development
GD Ogle, GA Gregory, F Wang, TIG Robinson… - Current Diabetes …, 2023 - Springer
Abstract Purpose of the Review Current global information on incidence, prevalence, and
mortality of type 1 diabetes (T1D) is limited, particularly in low-and middle-income countries …
mortality of type 1 diabetes (T1D) is limited, particularly in low-and middle-income countries …
[HTML][HTML] Sarm1 knockout prevents type 1 diabetic bone disease in females independent of neuropathy
Patients with diabetes have a high risk of developing skeletal diseases accompanied by
diabetic peripheral neuropathy (DPN). In this study, we isolated the role of DPN in skeletal …
diabetic peripheral neuropathy (DPN). In this study, we isolated the role of DPN in skeletal …
Can type 1 diabetes be an unexpected complication of obesity?
P Oboza, N Ogarek… - Frontiers in …, 2023 - frontiersin.org
Type 1 diabetes (T1D) is one of the most common chronic autoimmune diseases,
characterized by absolute insulin deficiency caused via inflammatory destruction of the …
characterized by absolute insulin deficiency caused via inflammatory destruction of the …
Efficacy of combination therapy with GABA, a DPP-4i and a PPI as an adjunct to insulin therapy in patients with type 1 diabetes
A Rabinovitch, D Koshelev… - Frontiers in …, 2023 - frontiersin.org
Introduction The purpose of this retrospective clinic chart review study was to determine the
potential of a combination therapy (CT) consisting of γ-aminobutyric acid (GABA), a …
potential of a combination therapy (CT) consisting of γ-aminobutyric acid (GABA), a …
Consensus Guidance for Monitoring Individuals With Islet Autoantibody–Positive Pre-Stage 3 Type 1 Diabetes
M Phillip, P Achenbach, A Addala… - Diabetes …, 2024 - diabetesjournals.org
Given the proven benefits of screening to reduce diabetic ketoacidosis (DKA) likelihood at
the time of stage 3 type 1 diabetes diagnosis, and emerging availability of therapy to delay …
the time of stage 3 type 1 diabetes diagnosis, and emerging availability of therapy to delay …
Type 1 diabetes impairs endothelium-dependent relaxation via increasing endothelial cell glycolysis through advanced glycation end products, PFKFB3, and Nox1 …
BACKGROUND: Type 1 diabetes (T1D) is a major cause of endothelial dysfunction.
Although cellular bioenergetics has been identified as a new regulator of vascular function …
Although cellular bioenergetics has been identified as a new regulator of vascular function …
Sensor-Based Glucose Metrics during Different Diet Compositions in Type 1 Diabetes—A Randomized One-Week Crossover Trial
KB Kristensen, AG Ranjan, OM McCarthy, RM Bracken… - Nutrients, 2024 - mdpi.com
By reducing carbohydrate intake, people with type 1 diabetes may reduce fluctuations in
blood glucose, but the evidence in this area is sparse. The aim of this study was to …
blood glucose, but the evidence in this area is sparse. The aim of this study was to …