Screening and prevention of type 1 diabetes: Where are we?

KM Simmons, EK Sims - The Journal of Clinical Endocrinology & …, 2023 - academic.oup.com
A diagnosis of type 1 diabetes (T1D) and the subsequent requirement for exogenous insulin
treatment is associated with considerable acute and chronic morbidity and a substantial …

Appropriate glycemic management protects the germline but not the uterine environment in hyperglycemia

A Zhao, H Jiang, AR Palomares, A Larsson, W He… - EMBO …, 2024 - embopress.org
Emerging evidence indicates that parental diseases can impact the health of subsequent
generations through epigenetic inheritance. Recently, it was shown that maternal diabetes …

[HTML][HTML] Celiac disease–related conditions: who to test?

F Zingone, JC Bai, C Cellier, JF Ludvigsson - Gastroenterology, 2024 - Elsevier
Celiac disease (CeD) is a chronic immune-mediated condition triggered by gluten
consumption in genetically predisposed individuals. Approximately 1% of the general …

[HTML][HTML] The role of the interferon/JAK-STAT axis in driving islet HLA-I hyperexpression in type 1 diabetes

MA Russell, SJ Richardson, NG Morgan - Frontiers in Endocrinology, 2023 - frontiersin.org
The hyperexpression of human leukocyte antigen class I (HLA-I) molecules on pancreatic
beta-cells is widely accepted as a hallmark feature of type 1 diabetes pathogenesis. This …

[HTML][HTML] Serum Cytokines and Growth Factors in Subjects with Type 1 Diabetes: Associations with Time in Ranges and Glucose Variability

VV Klimontov, KR Mavlianova, NB Orlov, JF Semenova… - Biomedicines, 2023 - mdpi.com
The detrimental effect of hyperglycemia and glucose variability (GV) on target organs in
diabetes can be implemented through a wide network of regulatory peptides. In this study …

[PDF][PDF] ISPAD Clinical Practice Consensus Guidelines 2022: Management of the child, adolescent, and young adult with diabetes in limited resource settings.

A Virmani, SJ Brink, A Middlehurst, F Mohsin… - Pediatric …, 2022 - researchgate.net
The child, adolescent and young adult with diabetes should receive optimal care according
to the principles and recommendations described in the respective chapters of the ISPAD …

A skin care program to prevent skin problems due to diabetes devices in children and adolescents: a cluster-controlled intervention study

AK Berg, AC Grauslund, F Sørensen… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE Diabetes devices that deliver insulin and measure blood glucose levels are
cornerstones in modern treatment of type 1 diabetes. However, their use is frequently …

[HTML][HTML] Early retinal microvascular alterations in young type 1 diabetic patients without clinical retinopathy

AO Dan, A Ștefănescu-Dima, AT Bălășoiu, I Puiu… - Diagnostics, 2023 - mdpi.com
The purpose of this study is to identify and quantify preclinical changes with the help of
optical coherence tomography angiography (OCTA) within the retinal microcirculation of …

New advances in type 1 diabetes

S Subramanian, F Khan, IB Hirsch - bmj, 2024 - bmj.com
Type 1 diabetes is an autoimmune condition resulting in insulin deficiency and eventual loss
of pancreatic β cell function requiring lifelong insulin therapy. Since the discovery of insulin …

[HTML][HTML] A systematic review of the association of Type I diabetes with sensorineural hearing loss

R Mittal, K McKenna, G Keith, JRN Lemos, J Mittal… - Plos one, 2024 - journals.plos.org
Objectives Type 1 diabetes (T1D) has been associated with several comorbidities such as
ocular, renal, and cardiovascular complications. However, the effect of T1D on the auditory …