Diabetes mellitus, a prevalent global health challenge, significantly impacts societal and
economic well-being. Islet transplantation is increasingly recognized as a viable treatment …

Type 1 diabetes incidence has increased worldwide, although the long-term trends on
pediatric type 1 diabetes in Japan remain elusive. To investigate the incidence and secular …

Background Because of the scarcity, high cost, and severe side effects of current
medications, it is necessary to discover novel, safe, and affordable anti-diabetic drugs. The …

Introduction Despite the improvements of insulin therapy, people with type 1 diabetes (T1D)
still suffer from a decreased quality of life and life expectancy. The search toward a cure for …

Abstract Background Type 1 diabetes (T1D) is a challenging autoimmune disease,
characterized by an immune system assault on insulin-producing β-cells. As insulin …

Background: Adult-onset type 1 diabetes is frequently misdiagnosed as type 2 diabetes,
leading to inappropriate care (1). Emerging data suggest that up to 62% of type 1 diabetes …

Diabetes, characterized as a well-known chronic metabolic syndrome, with its associated
complications pose a substantial and escalating health and healthcare challenge on a …

Background: Hypoglycemia remains a challenge for roughly 25% of people with type 1
diabetes (T1D) despite using advanced technologies such as continuous glucose monitors …

Type 1 diabetes mellitus (T1D) is an autoimmune disease caused by the destruction of
insulin-producing β-cells in the pancreas by cytotoxic T-cells. To date, there are no drugs …

Diabetes is a public health crisis, and diabetes-related health and economic burdens have
been rising globally over the past decades, with the growth being the most striking in low …