Breast cancer heterogeneity and its implication in personalized precision therapy

L Guo, D Kong, J Liu, L Zhan, L Luo, W Zheng… - … hematology & oncology, 2023 - Springer
Breast cancer heterogeneity determines cancer progression, treatment effects, and
prognosis. However, the precise mechanism for this heterogeneity remains unknown owing …

The great immune escape: understanding the divergent immune response in breast cancer subtypes

SS Onkar, NM Carleton, PC Lucas, TC Bruno, AV Lee… - Cancer discovery, 2023 - AACR
Breast cancer, the most common type of cancer affecting women, encompasses a collection
of histologic (mainly ductal and lobular) and molecular subtypes exhibiting diverse clinical …

Immunotherapy approaches for breast cancer patients in 2023

LA Emens, S Loi - Cold Spring Harbor …, 2023 - perspectivesinmedicine.cshlp.org
Immunotherapy, particularly agents targeting the immunoregulatory PD-1/PD-L1 axis,
harnesses the power of the immune system to treat cancer, with unique potential for a …

Entinostat, nivolumab and ipilimumab for women with advanced HER2-negative breast cancer: a phase Ib trial

ET Roussos Torres, WJ Ho, L Danilova, JA Tandurella… - Nature Cancer, 2024 - nature.com
We report the results of 24 women, 50%(N= 12) with hormone receptor-positive breast
cancer and 50%(N= 12) with advanced triple-negative breast cancer, treated with …

Landscape of the peripheral immune response induced by local microwave ablation in patients with breast cancer

W Zhou, M Yu, X Mao, H Pan, X Tang… - Advanced …, 2022 - Wiley Online Library
Minimally invasive thermal therapies have been attempted in the treatment of breast cancer,
and the immune response induced by these therapies has not been fully reported. A clinical …

Immunotherapy in breast cancer: an overview of current strategies and perspectives

V Debien, A De Caluwé, X Wang… - NPJ Breast …, 2023 - nature.com
Recent progress in immunobiology has led the way to successful host immunity
enhancement against breast cancer. In triple-negative breast cancer, the combination of …

Potentialities and challenges of mRNA vaccine in cancer immunotherapy

LJ Duan, Q Wang, C Zhang, DX Yang… - Frontiers in …, 2022 - frontiersin.org
Immunotherapy has become the breakthrough strategies for treatment of cancer in recent
years. The application of messenger RNA in cancer immunotherapy is gaining tremendous …

Huaier Induces Immunogenic Cell Death Via CircCLASP1/PKR/eIF2α Signaling Pathway in Triple Negative Breast Cancer

C Li, X Wang, T Chen, W Li, X Zhou, L Wang… - Frontiers in Cell and …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is the most lethal breast cancer subtype owing to the
lack of targeted therapeutic strategies. Immunogenic cell death (ICD), a modality of …

The role of immune checkpoint inhibition in triple negative breast cancer

K Tarekegn, M Keskinkilic, TJ Kristoff… - Expert Review of …, 2023 - Taylor & Francis
Introduction Immunotherapy has revolutionized cancer treatment, including TNBC, which
has limited options of treatment and poor prognosis. ICIs studied in TNBC include …

Estrogens, cancer and immunity

I Orzołek, J Sobieraj, J Domagała-Kulawik - Cancers, 2022 - mdpi.com
Simple Summary In this review, we present current knowledge of sex hormones in the
process of development of malignant diseases. The impact of sex hormones on immune …