[HTML][HTML] The Role of Noncoding RNA in the Transmission and Pathogenicity of Flaviviruses

X Zhang, Y Li, Y Cao, Y Wu, G Cheng - Viruses, 2024 - mdpi.com
Noncoding RNAs (ncRNAs) constitute a class of RNA molecules that lack protein-coding
capacity. ncRNAs frequently modulate gene expression through specific interactions with …

[HTML][HTML] Strain variation can significantly modulate the miRNA Response to Zika virus infection

S Ramphan, C Chumchanchira, W Sornjai… - International Journal of …, 2023 - mdpi.com
Zika virus (ZIKV) is a mosquito-transmitted virus that has emerged as a major public health
concern due to its association with neurological disorders in humans, including …

OTUD4 regulates metastasis and chemoresistance in melanoma by stabilizing Snail1

Y Gao, J Tang, X Ma, C Zhang, L Huang… - Journal of Cellular …, 2023 - Wiley Online Library
Melanoma is the most aggressive form of skin cancer with rapidly increased incidence
worldwide especially in the Caucasian population. Surgical excision represents the curative …

Deubiquitinating enzyme OTUD4 regulates metastasis in triple-negative breast cancer by stabilizing Snail1

X Ma, R Wan, Y Wen, T Liu, Y Song, Y Zhu - Experimental Cell Research, 2024 - Elsevier
Metastasis is the primary cause of cancer-related deaths and remains poorly understood.
Deubiquitinase OTU domain containing 4 (OTUD4) has been reported to regulate antiviral …

[HTML][HTML] Integrated analysis to study the interplay between post-translational modifications (PTM) in hepatitis C virus proteins and hepatocellular carcinoma (HCC) …

A Ikram, B Rauff, B Alzahrani, FM Awan, A Obaid… - Scientific Reports, 2022 - nature.com
Many PTMs dysregulation is known to be the major cause of many cancers including HCV
induced HCC. PTMs of hepatitis C virus (HCV) regions NS3/4A, NS5A and NS5B are crucial …

Hsa_circ_0007321 regulates Zika virus replication through miR-492/NFKBID/NF-κB signaling pathway

L Kang, H Xie, H Ye, AJ Jeyarajan, CA Warner… - Journal of …, 2023 - Am Soc Microbiol
ABSTRACT Circular RNAs (CircRNAs) have been shown to play a critical role in regulating
viral infection and replication. We performed RNA sequencing to identify differentially …

[HTML][HTML] Berberine inhibitory action against zika and dengue viruses in cell cultures

DA Giannone, LE Piccini, JE Brunetti… - Acta …, 2023 - frontierspartnerships.org
Berberine (BBR) is a plant derived isoquinoline alkaloid that displays a great variety of
biological activities. In this study we showed that BBR exhibits a strong antiviral activity with …

UMP‐CMP kinase 2 inhibits ZIKV replication through activation of type I IFN signaling pathway

Y Zhu, Q Tan, Y Shi, Q Li, S Li, W Wen… - Journal of Medical …, 2024 - Wiley Online Library
Cytidine/uridine monophosphate kinase 2 (UMP‐CMP kinase 2, CMPK2) has been reported
as an antiviral interferon‐stimulated gene (ISG). We previously observed that the expression …

Protective Effects of Caffeine on Chikungunya and Zika Virus Infections: An in Vitro and in Silico Study

Y de Jesús López Medina… - Chemistry & …, 2023 - Wiley Online Library
Infection by viruses Chikungunya (CHIKV) and Zika (ZIKV) continue to be serious problems
in tropical and subtropical areas of the world. Here, we evaluated the antiviral and virucidal …

Research progress on miRNAs function in the interaction between human infectious viruses and hosts: A review

X Wang, W Zhao - Biomolecules and Biomedicine, 2024 - bjbms.org
MicroRNAs (miRNAs) represent a class of non-coding small RNAs that are prevalent in
eukaryotes, typically comprising approximately 22 nucleotides, and have the ability to post …