Hyperpolarized (HP) xenon‐129 (129Xe) brain MRI is a promising imaging modality
currently under extensive development. HP 129Xe is nontoxic, capable of dissolving in …

Hypoxic-ischemic encephalopathy (HIE) is a major cause of newborn brain damage
stemming from a lack of oxygenated blood flow in the neonatal period. Twenty-five to fifty …

Purpose Imaging of the different resonances of hyperpolarized 129Xe in the brain and lungs
was performed using a 3D sampling density‐weighted MRSI technique in healthy …

Objectives Design and build a portable xenon-129 (129Xe) hyperpolariser for clinically
accessible 129Xe lung MRI. Methods The polariser system consists of six main functional …

Purpose To demonstrate the feasibility of 129Xe chemical shift saturation recovery (CSSR)
combined with spiral‐IDEAL imaging for simultaneous measurement of the time‐course of …

Purpose To demonstrate the possibility of performing multi‐slice in‐vivo human brain MRI
using hyperpolarized (HP) xenon‐129 (129Xe) in two different orientations and to calculate …

Ultrasound in combination with the introduction of microbubbles into the vasculature
effectively opens the blood brain barrier (BBB) to allow the passage of therapeutic agents …

Purpose To evaluate the effect of an initial 90° depolarization RF pulse on the dissolved‐
phase hyperpolarized (HP) xenon‐129 (129Xe) brain imaging and to compare the SNR …

The central nervous system is characterized by a peculiar vascularization termed blood-
brain barrier (BBB), which regulates the exchange of cells and molecules between the …

Background The feasibility of imaging hyperpolarized 129 Xe dissolved in brain tissue
following inhalation of xenon gas in the lungs has recently been demonstrated in humans …