The controversial nature of the CB1 receptor antagonist, SR141716A, in the guineapig
small intestine was investigated by comparing it with four analogues of Δ8 …

1 This study investigated whether (a) cannabinoid CB1 receptor knockout (CB1−/−) mice
displayed altered gastrointestinal transit and (b) cannabinoid CB1 and opioid receptors …

The purpose of the present study was to examine whether cannabinoid receptor agonists
influence spontaneous contractile activity of longitudinal muscle in mouse ileum in vitro …

The identification of endocannabinoids and cannabinoid CB1 receptors in key areas of the
intestinal wall, such as cholinergic neurons, supports a role for cannabinoids in the control of …

The effects of the cannabinoid receptor agonist Win 55,212-2 and of the competitive
cannabinoid receptor antagonist SR 141716A on the electrically-evoked peristalsis of …

Background In the absence of pathology, cannabinoidinduced depression of
gastrointestinal (GI) motility is thought to be mediated primarily by CB1 receptors, whereas …

US7485730B2 - Pharmaceutical compounds - Google Patents US7485730B2 - Pharmaceutical
compounds - Google Patents Pharmaceutical compounds Download PDF Info Publication …

It is well accepted that endogenous cannabinoids and CB1 receptors are involved in the
regulation of smooth muscle contractility and intestinal motility, through a mechanism mainly …

The cannabinoid CB1 receptor antagonist, SR 141716 (Rimonabant), has been reported to
stimulate, when acutely administered, intestinal motility in mice. The present study was …

Cannabis stimulates appetite and food intake. This property has been exploited to benefit
AIDS and cancer patients suffering from wasting disease, by administering the whole plant …