Immunomodulatory properties of CD38 antibodies and their effect on anticancer efficacy in multiple myeloma

K Bisht, T Fukao, M Chiron, P Richardson… - Cancer …, 2023 - Wiley Online Library
Background CD38 has been established as an important therapeutic target for multiple
myeloma (MM), for which two CD38 antibodies are currently approved—daratumumab and …

[HTML][HTML] Therapy in the Course of Kidney Graft Rejection—Implications for the Cardiovascular System—A Systematic Review

J Mizera, J Pilch, U Giordano, M Krajewska, M Banasik - Life, 2023 - mdpi.com
Kidney graft failure is not a homogenous disease and the Banff classification distinguishes
several types of graft rejection. The maintenance of a transplant and the treatment of its …

Single-Cell Heterogeneity Restorative Chimeric Engineering Nanoparticles for Alleviating Antibody-Mediated Allograft Injury

J Lin, J Lv, X Yu, X Xue, S Yu, H Wang… - ACS Applied Materials …, 2023 - ACS Publications
Disturbance of single-cell transcriptional heterogeneity is an inevitable consequence of
persistent donor-specific antibody (DSA) production and allosensitization. However …

[HTML][HTML] Early Exposure of Kidney Transplant Recipients with Chronic Antibody-Mediated Rejection to Tocilizumab—A Preliminary Study

C Arrivé, M Jacquet, E Gautier-Veyret, T Jouve… - Journal of Clinical …, 2023 - mdpi.com
Tocilizumab prevents clinical worsening of chronic antibody-mediated rejection (CAMR) of
kidney transplant recipients. Optimization of this treatment is necessary. We identified the …

Graft Protective and Intercellular Immunomodulatory Effects by Adoptive Transfer of an Agonistic Anti-BTLA mAb (3C10) Induced CD4+ CD25+ Regulatory T Cells in …

H Masaoka, Y Yamamoto, M Uchiyama, K Iguchi… - Transplantation …, 2024 - Elsevier
Background We demonstrated that an agonistic anti-B and T lymphocyte attenuator antibody
(3C10) prolonged cardiac survival by inducing regulatory T cells (Treg). However, the …

贵州省首例跨血型亲属活体肾移植围手术期的护理

许艳艳, 牛玉林, 丁蓓 - 实用临床医药杂志 - jcmp.yzu.edu.cn
ABO 血型不相符活体肾移植是目前扩大活体供体库的常规方法. 尽管肾移植术后排斥反应,
感染等并发症相关报道较多, 但随着免疫抑制剂方案和脱敏治疗的发展, 肾脏移植物和患者的 …

TDM of belatacept and other biologicals in transplantation.

S Bergan, NT Vethe - Authorea Preprints, 2024 - advance.sagepub.com
In solid organ transplantation biologicals like recombinant therapeutic proteins, monoclonal
antibodies, fusion proteins and conjugates are increasingly used for immunosuppression …

Landscape of the Immune Infiltration and Identification of Molecular Diagnostic Markers Associated With Immune Cells in Patients With Kidney Transplantation

Z Xu, X Sun, X Ma, B Tao, J Wu, Y He, Y Zhao, H Mao… - 2024 - researchsquare.com
Rejection seriously affects the success of kidney transplantation. However, the molecular
mechanism of the occurrence of rejection remains unclear. Firstly, GSE21374 and …

Perioperative nursing for kidney transplantation from a related living-donor with blood-type mismatched: the first case in Guizhou Province

XU Yanyan, NIU Yulin, D Bei - Journal of Clinical Medicine in Practice - jcmp.yzu.edu.cn
Living kidney transplantation with ABO blood type mismatch is currently a routine method for
expanding the living donor unit. Although there have been many reports of complications …

[PDF][PDF] Is Lack of Consensus on the Management of Chronic Active Antibody-Mediated Rejection Harming Renal Transplant Recipients?

L Rostaing - emjreviews.com
Given this lack of consensus, what does the clinical landscape look like for patients with
CABMR? By conducting an online survey with European nephrologists, transplant …