Substance use disorders (SUDs) are conditions in which the use of legal or illegal
substances, such as nicotine, alcohol or opioids, results in clinical and functional …

Epigenetic modifications are increasingly recognized to play a role in the etiology and
pathophysiology of schizophrenia and other psychiatric disorders with developmental …

Background Immunotherapy has become an important treatment option for patients with
advanced non-small cell lung cancer (NSCLC). At present, none of these existing …

Epigenetic mechanisms involve the placing (writing) or removal (erasing) of histone
modifications that allow heterochromatin to transition to the open, activated euchromatin …

Epigenome‐wide association study (EWAS) has been applied to analyze DNA methylation
variation in complex diseases for a decade, and epigenome as a research target has …

Whether glyphosate-based herbicides (GBHs) are more potent than glyphosate alone at
activating cellular mechanisms, which drive carcinogenesis remain controversial. As GBHs …

Background Childhood adversity is a potent determinant of health across development and
is associated with altered DNA methylation signatures, which might be more common in …

In utero exposure to maternal tobacco smoking is the leading cause of birth complications in
addition to being associated with later impairment in child's development. Epigenetic …

Background The inflammatory bowel diseases, Crohn's disease and ulcerative colitis are
related multifactorial diseases. Their pathogenesis is influenced by each individual's …

Although tobacco smoking is a risk factor for lung adenocarcinoma (LUAD), the mechanisms
by which tobacco smoking induces LUAD development remain elusive. Histone methylation …