Anomalous transport in the crowded world of biological cells

F Höfling, T Franosch - Reports on Progress in Physics, 2013 - iopscience.iop.org
A ubiquitous observation in cell biology is that the diffusive motion of macromolecules and
organelles is anomalous, and a description simply based on the conventional diffusion …

The restaurant at the end of the random walk: recent developments in the description of anomalous transport by fractional dynamics

R Metzler, J Klafter - Journal of Physics A: Mathematical and …, 2004 - iopscience.iop.org
Fractional dynamics has experienced a firm upswing during the past few years, having been
forged into a mature framework in the theory of stochastic processes. A large number of …

Intermittent search strategies

O Bénichou, C Loverdo, M Moreau, R Voituriez - Reviews of Modern Physics, 2011 - APS
This review examines intermittent target search strategies, which combine phases of slow
motion, allowing the searcher to detect the target, and phases of fast motion during which …

Physical nature of bacterial cytoplasm

I Golding, EC Cox - Physical review letters, 2006 - APS
We track the motion of individual fluorescently labeled mRNA molecules inside live E. coli
cells. We find that the motion is subdiffusive, with an exponent that is robust to physiological …

Anomalous diffusion of proteins due to molecular crowding

DS Banks, C Fradin - Biophysical journal, 2005 - cell.com
We have studied the diffusion of tracer proteins in highly concentrated random-coil polymer
and globular protein solutions imitating the crowded conditions encountered in cellular …

Rheology of soft materials

DTN Chen, Q Wen, PA Janmey… - Annu. Rev. Condens …, 2010 - annualreviews.org
Research on soft materials, including colloidal suspensions, glasses, pastes, emulsions,
foams, polymer networks, liquid crystals, granular materials, and cells, has captured the …

Anomalous diffusion and ergodicity breaking in heterogeneous diffusion processes

AG Cherstvy, AV Chechkin, R Metzler - New Journal of Physics, 2013 - iopscience.iop.org
We demonstrate the non-ergodicity of a simple Markovian stochastic process with space-
dependent diffusion coefficient D (x). For power-law forms D (x)≃| x| α, this process yields …

Probing short-range protein Brownian motion in the cytoplasm of living cells

C Di Rienzo, E Gratton, F Beltram, F Cardarelli - Biophysical Journal, 2015 - cell.com
The translational motion of small molecules in cells appears to be suppressed compared to
what is observed in dilute solutions. Although, the rotation of small proteins is almost …

Light at work: The use of optical forces for particle manipulation, sorting, and analysis

A Jonáš, P Zemanek - Electrophoresis, 2008 - Wiley Online Library
We review the combinations of optical micro‐manipulation with other techniques and their
classical and emerging applications to non‐contact optical separation and sorting of micro …

Microrheology, stress fluctuations, and active behavior of living cells

AWC Lau, BD Hoffman, A Davies, JC Crocker… - Physical review …, 2003 - APS
We report the first measurements of the intrinsic strain fluctuations of living cells using a
recently developed tracer correlation technique along with a theoretical framework for …