Amino acid PET in neurooncology

N Galldiks, P Lohmann, GR Fink… - Journal of Nuclear …, 2023 - Soc Nuclear Med
For decades, several amino acid PET tracers have been used to optimize diagnostics in
patients with brain tumors. In clinical routine, the most important clinical indications for amino …

A bis-boron boramino acid PET tracer for brain tumor diagnosis

Z Li, J Chen, Z Kong, Y Shi, M Xu, BS Mu, N Li… - European Journal of …, 2024 - Springer
Purpose Boramino acids are a class of amino acid biomimics that replace the carboxylate
group with trifluoroborate and can achieve the 18F-labeled positron emission tomography …

[HTML][HTML] Comparing [18F] FET PET and [18F] FDOPA PET for glioma recurrence diagnosis: a systematic review and meta-analysis

P Yu, Y Wang, F Su, Y Chen - Frontiers in Oncology, 2024 - frontiersin.org
Purpose The purpose of our meta-analysis and systematic review was to evaluate and
compare the diagnostic effectiveness of [18F] FET PET and [18F] FDOPA PET in detecting …

Manufacturing 6-[18F]Fluoro-L-DOPA via Flow Chemistry-Enhanced Photoredox Radiofluorination

X Wu, W Chen, H Deng, L Wang, DA Nicewicz… - Organic …, 2024 - ACS Publications
In this study, we introduce a practical methodology for the synthesis of PET probes by
seamlessly combining flow chemistry with photoredox radiofluorination. The clinical PET …

Added value of [18F]FDOPA PET to the management of high-grade glioma patients after their initial treatment: a prospective multicentre study

J Darcourt, D Chardin, V Bourg, J Gal… - European Journal of …, 2023 - Springer
Abstract Background Diagnostic value of 3, 4-dihydroxy-6-[18F] fluoro-L-phenylalanine
([18F] FDOPA) PET in patients with suspected recurrent gliomas is recognised. We …

Individualized discrimination of tumor progression from treatment-related changes in different types of adult-type diffuse gliomas using [11C]methionine PET

Q Chen, K Wang, X Ren, X Zhao, Q Chen, D Fan… - Journal of Neuro …, 2023 - Springer
Purpose This study aimed to assess the ability of [11C] methionine (MET) PET in
distinguishing between tumor progression (TP) and treatment-related changes (TRCs) …

[HTML][HTML] Amino-acid PET as a prognostic tool after post Stupp protocol temozolomide therapy in high-grade glioma patients

A Zinsz, S Ahrari, J Becker, A Mortada, V Roch… - Journal of Neuro …, 2024 - Springer
Purpose This study aimed to evaluate the prognostic performance of amino-acid PET in high-
grade gliomas (HGG) patients at the time of temozolomide (TMZ) treatment discontinuation …

Contribution of nuclear medicine to the diagnosis and management of primary brain tumours

T Horowitz, E Tabouret, T Graillon, B Salgues… - Revue …, 2023 - Elsevier
Positron emission tomography (PET) is a powerful tool that can help physicians manage
primary brain tumours at diagnosis and follow-up. In this context, PET imaging is used with …