Introduction The treatment of metastatic melanoma has been revolutionized by the
introduction of immune checkpoint inhibitors and BRAF/MEK inhibition. Nevertheless, almost …

This case report describes the occurrence of hyperbilirubinemia as a complication of
metastatic melanoma. A 72-year-old male patient was diagnosed with BRAF V600E-mutated …

Das Melanom ist ein hoch aggressiver Hauttumor mit dem Beinamen „schwarzer Hautkrebs
“, da er von den pigmentbildenden Zellen (Melanozyten) ausgeht. Die Tumoren neigen zu …

Methods: PubMed, Scopus and Embase databases were systematically queried to obtain
records pertaining to the etiology of and treatment for MBM. Clinical trial databases were …

ABSTRACT Objectives Immune checkpoint inhibitors (ICIs) are one of the most promising
approaches toward advanced melanoma. Here, we aimed to perform a meta-analysis of …

Simple Summary Sex is an important variable that can affect immunity, both in the cellular
and humoral sense. This may result from differences in genes, hormones, the environment …

Melanoma, a malignant neoplasm originating from melanocytes, stands as one of the most
prevalent cancers globally, ranking fifth in terms of estimated new cases in recent years. Its …

The mitogen-activated protein kinase (MAPK) pathway is essential for cellular proliferation,
growth, and survival. Constitutive activation of this pathway by BRAF mutations can cause …

Melanoma, a highly aggressive skin cancer, is characterized by rapid progression and high
mortality. Recent advances in molecular pathogenesis have shed light on genetic and …

There is currently no consensus to determine which advanced melanoma patients will
benefit from targeted therapy, immunotherapy, or a combination of both, highlighting the …