Growing life expectancy will contribute to the on-going shift towards a world population
increasingly comprised of elderly individuals. This demographic shift is associated with a …

Inflammatory bowel diseases, with an increasing incidence, pose a significant health
burden. Although there have been significant advances in the treatment of IBD, more …

Retinal ischemic injuries play an important role in the pathogenesis of several eye disorders.
Inflammation and oxidative stress are key players in ischemic injuries. Following retinal …

This study evaluated the potential neuroprotective effect of azithromycin (AZ) intraperitoneal
injections in male C57Bl/6 (wild type, WT) and female NOD scid gamma (NSG) mice …

Purpose: This study investigated the neuroprotective effects of administration of ROCK
inhibitor E212 on ischemic optic neuropathy. Methods: Rats received an intravitreal injection …

Purpose Nonarteritic anterior ischemic optic neuropathy (NAION) is the second most
common form of optic neuropathy. Most patients show no improvement over time. Until now …

Non-arteritic anterior ischemic optic neuropathy (NAION) is characterized by the progressive
and irreversible death of retinal ganglion cells (RGCs) which is caused by the insufficient …

非动脉炎性前部缺血性视神经病变(NAION) 是50 岁以上人群常见的急性视神经病变, 以突发,
单眼, 无痛性视力下降为特征. 多种治疗方法被尝试用于治疗NAION, 包括药物治疗和手术治疗 …

Purpose.: To evaluate the effect of bevacizumab, a VEGF inhibitor, on optic nerve edema
and retinal ganglion cell (RGC) loss in a mouse model of optic nerve crush (ONC). Methods …

Ischemic optic neuropathy is a major cause of significantly reduced vision (1–3). It may be
arteritic (AAION) or non-arteritic (NA-AION), anterior or posterior. NA-AION, the most …