[HTML][HTML] In Vitro Models for Neuropathic Pain Phenotypic Screening in Brain Therapeutics

AL Martínez, J Brea, D López, N Cosme, M Barro… - Pharmacological …, 2024 - Elsevier
The discovery of brain therapeutics faces a significant challenge due to the low
translatability of preclinical results into clinical success. To address this gap, several efforts …

Assessment of corneal nerve regeneration after axotomy in a compartmentalized microfluidic chip model with automated 3D high resolution live-imaging

N Bonneau, A Potey, F Blond, C Guerin… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction Damage to the corneal nerves can result in discomfort and chronic pain,
profoundly impacting the quality of life of patients. Development of novel in vitro method is …

In vitro models for neuropathic pain phenotypic screening in brain therapeutics

AL Martínez Rodríguez, JM Brea Floriani, D López… - 2024 - minerva.usc.es
The discovery of brain therapeutics faces a significant challenge due to the low
translatability of preclinical results into clinical success. To address this gap, several efforts …

[图书][B] High-capacity in vitro models for the assessment of pain-related mechanisms

L Moll - 2024 - openarchive.ki.se
Chronic pain affects one in five people. Yet, new efficient drugs with fewer adverse effects
remain an unmet need for chronic pain. In vitro models that closer recapitulate relevant …