Beyond E-cadherin: roles of other cadherin superfamily members in cancer

F Van Roy - Nature Reviews Cancer, 2014 - nature.com
Abstract Loss of cadherin 1 (CDH1; also known as epithelial cadherin (E-cadherin)) is used
for the diagnosis and prognosis of epithelial cancers. However, it should not be ignored that …

Putative biomarkers for cervical cancer: SNVs, methylation and expression profiles

MFS Cardoso, CHM Castelletti, JL de Lima-Filho… - … Research/Reviews in …, 2017 - Elsevier
Cervical cancer is primarily caused by Human papillomavirus (HPV) infection, but other
factors such as smoking habits, co-infections and genetic background, can also contribute to …

[HTML][HTML] Role of adiponectin and its receptors in cancer

S Obeid, L Hebbard - Cancer biology & medicine, 2012 - ncbi.nlm.nih.gov
Adiponectin (APN), a novel hormone/cytokine derived from adipocyte tissue, is involved in
various physiological functions. Genetics, nutrition, and adiposity are factors contributing to …

[HTML][HTML] Cadherin 13 inhibits pancreatic cancer progression and epithelial-mesenchymal transition by Wnt/β-catenin signaling

D Xu, H Yuan, Z Meng, C Yang, Z Li, M Li… - Journal of …, 2020 - ncbi.nlm.nih.gov
Abstract Cadherin 13 (CDH13) is an atypical cadherin that exerts tumor-suppressive effects
on cancers derived from epithelial cells. Although the CDH13 promoter is frequently …

Designing a multicellular organotypic 3D liver model with a detachable, nanoscale polymeric Space of Disse

AL Larkin, RR Rodrigues, TM Murali… - … Engineering Part C …, 2013 - liebertpub.com
The design of in vitro models that mimic the stratified multicellular hepatic microenvironment
continues to be challenging. Although several in vitro hepatic cultures have been shown to …

[HTML][HTML] Kinectin1 depletion promotes EGFR degradation via the ubiquitin-proteosome system in cutaneous squamous cell carcinoma

J Ma, S Ma, Y Zhang, Y Shen, L Huang, T Lu… - Cell Death & …, 2021 - nature.com
Abstract Depletion of kinectin1 (KTN1) provides a potential strategy for inhibiting
tumorigenesis of cutaneous squamous cell carcinoma (cSCC) via reduction of epidermal …

T-cadherin promotes autophagy and survival in vascular smooth muscle cells through MEK1/2/Erk1/2 axis activation

E Kyriakakis, A Frismantiene, B Dasen, D Pfaff… - Cellular signalling, 2017 - Elsevier
Autophagy is an evolutionary conserved intracellular catabolic process of vital importance to
cell and tissue homeostasis. Autophagy is implicated in the pathogenesis of atherosclerosis …

Overexpression of T-cadherin inhibits the proliferation of oral squamous cell carcinoma through the PI3K/AKT/mTOR intracellular signalling pathway

Q Wang, X Zhang, X Song, L Zhang - Archives of oral biology, 2018 - Elsevier
Objective To evaluate T-cadherin gene expression in patients with oral squamous cell
carcinoma (OSCC) and explore its effect on the proliferation of OSCC. Additionally, the …

[HTML][HTML] T-cadherin loss promotes experimental metastasis of squamous cell carcinoma

M Philippova, D Pfaff, E Kyriakakis, SA Buechner… - European journal of …, 2013 - Elsevier
T-cadherin is gaining recognition as a determinant for the development of incipient invasive
squamous cell carcinoma (SCC). However, effects of T-cadherin expression on the …

[HTML][HTML] CDH13 is a prognostic biomarker and a potential therapeutic target for patients with clear cell renal cell carcinoma

Y Shao, W Li, L Zhang, B Xue, Y Chen… - American Journal of …, 2022 - ncbi.nlm.nih.gov
CDH13 is an atypical member of the cadherin family and is closely related to the
clinicopathological factors and prognosis of many types of cancer. However, the role of …