Parkinson's disease in women and men: what's the difference?

S Cerri, L Mus, F Blandini - Journal of Parkinson's disease, 2019 - content.iospress.com
Increasing evidence points to biological sex as an important factor in the development and
phenotypical expression of Parkinson's disease (PD). Risk of developing PD is twice as high …

Prevalence and clinical aspects of mild cognitive impairment in Parkinson's disease: A meta‐analysis

C Baiano, P Barone, L Trojano… - Movement …, 2020 - Wiley Online Library
Mild cognitive impairment associated with Parkinson's disease (PD) is a risk factor for the
development of dementia. Despite the importance of early identification of mild cognitive …

Sex differences in movement disorders

S Meoni, A Macerollo, E Moro - Nature Reviews Neurology, 2020 - nature.com
In a range of neurological conditions, including movement disorders, sex-related differences
are emerging not only in brain anatomy and function, but also in pathogenesis, clinical …

Cognition deficits in Parkinson's disease: mechanisms and treatment

C Fang, L Lv, S Mao, H Dong, B Liu - Parkinson's disease, 2020 - Wiley Online Library
Parkinson's disease (PD) is the second most common progressive neurodegenerative
disorder mainly in middle‐elderly population, which represents diverse nonmotor symptoms …

Sex specific cognitive differences in Parkinson disease

TH Reekes, CI Higginson, CR Ledbetter… - npj Parkinson's …, 2020 - nature.com
Parkinson disease (PD) is a progressive neurodegenerative disorder that is 1.5 times more
common in males than in females. While motor progression tends to be more aggressive in …

Sex and gender differences in Alzheimer's disease, Parkinson's disease, and Amyotrophic Lateral Sclerosis: A narrative review

A Nicoletti, R Baschi, CE Cicero, S Iacono… - Mechanisms of ageing …, 2023 - Elsevier
Abstract Neurodegenerative diseases (NDs), including Alzheimer's disease (AD),
Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), exhibit high phenotypic …

Human iPSC-derived microglia carrying the LRRK2-G2019S mutation show a Parkinson's disease related transcriptional profile and function

S Ohtonen, L Giudice, H Jäntti, MF Fazaludeen… - Scientific Reports, 2023 - nature.com
Abstract LRRK2-G2019S is one of the most common Parkinson's disease (PD)-associated
mutations and has been shown to alter microglial functionality. However, the impact of …

Episodic recognition memory and the hippocampus in Parkinson's disease: a review

T Das, JJ Hwang, KL Poston - Cortex, 2019 - Elsevier
Parkinson's disease is a progressive neurodegenerative disorder of aging. The hallmark
pathophysiology includes the development of neuronal Lewy bodies in the substantia nigra …

Meta-analysis of cognition in Parkinson's disease mild cognitive impairment and dementia progression

ER Wallace, SC Segerstrom, CG van Horne… - Neuropsychology …, 2022 - Springer
Mild cognitive changes, including executive dysfunction, are seen in Parkinson's Disease
(PD). Approximately 30% of individuals with PD develop Parkinson's disease dementia …

Differences in the presentation and progression of Parkinson's disease by sex

H Iwaki, C Blauwendraat, HL Leonard… - Movement …, 2021 - Wiley Online Library
Background Previous studies reported various symptoms of Parkinson's disease (PD)
associated with sex. Some were conflicting or confirmed in only one study. Objectives We …