Biological activity of plant-based carvacrol and thymol and their impact on human health and food quality

NB Rathod, P Kulawik, F Ozogul, JM Regenstein… - Trends in Food Science …, 2021 - Elsevier
Background There is an increased consumer demand for products derived from natural
sources or containing natural compounds used to preserve or improve food quality and/or …

Phytosomes as innovative delivery systems for phytochemicals: A comprehensive review of literature

M Barani, E Sangiovanni, M Angarano… - International journal …, 2021 - Taylor & Francis
Nowadays, medicinal herbs and their phytochemicals have emerged as a great therapeutic
option for many disorders. However, poor bioavailability and selectivity might limit their …

Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer

S Mirzaei, MH Gholami, A Zabolian, H Saleki… - Pharmacological …, 2021 - Elsevier
As a phenolic acid compound, caffeic acid (CA) can be isolated from different sources such
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …

Polyvinyl alcohol based-drug delivery systems for cancer treatment

G Rivera-Hernández, M Antunes-Ricardo… - International Journal of …, 2021 - Elsevier
Polyvinyl alcohol (PVA) is a biodegradable semicrystalline synthetic polymer that has been
used for biomedical applications for several years. In the pharmaceutical area, PVA has …

Status and challenges of plant-anticancer compounds in cancer treatment

P Garcia-Oliveira, P Otero, AG Pereira, F Chamorro… - Pharmaceuticals, 2021 - mdpi.com
Nowadays, cancer is one of the deadliest diseases in the world, which has been estimated
to cause 9.9 million deaths in 2020. Conventional treatments for cancer commonly involve …

The Yin and Yang of exosome isolation methods: conventional practice, microfluidics, and commercial kits

SZ Shirejini, F Inci - Biotechnology Advances, 2022 - Elsevier
Exosomes are a subset of extracellular vesicles released from various cells, and they can be
found in different bodily fluids. Exosomes have been utilized as biomarkers to diagnose …

Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery

AB Buya, A Beloqui, PB Memvanga, V Préat - Pharmaceutics, 2020 - mdpi.com
Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …

Curcumin delivery mediated by bio-based nanoparticles: a review

M Moballegh Nasery, B Abadi, D Poormoghadam… - Molecules, 2020 - mdpi.com
Todays, nano-pharmaceutics is emerging as an important field of science to develop and
improve efficacy of different drugs. Although nutraceuticals are currently being utilized in the …

Anti-hepatocellular carcinoma biomolecules: molecular targets insights

N Juaid, A Amin, A Abdalla, K Reese, Z Alamri… - International journal of …, 2021 - mdpi.com
This report explores the available curative molecules directed against hepatocellular
carcinoma (HCC). Limited efficiency as well as other drawbacks of existing molecules led to …

Targeting multiple signaling pathways in cancer: The rutin therapeutic approach

Z Nouri, S Fakhri, K Nouri, CE Wallace, MH Farzaei… - Cancers, 2020 - mdpi.com
Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …