Understanding the impact of sex and gender in Alzheimer's disease: a call to action

RA Nebel, NT Aggarwal, LL Barnes, A Gallagher… - Alzheimer's & …, 2018 - Elsevier
Introduction Precision medicine methodologies and approaches have advanced our
understanding of the clinical presentation, development, progression, and management of …

Clinical epidemiology of Alzheimer's disease: assessing sex and gender differences

MM Mielke, P Vemuri, WA Rocca - Clinical epidemiology, 2014 - Taylor & Francis
With the aging of the population, the burden of Alzheimer's disease (AD) is rapidly
expanding. More than 5 million people in the US alone are affected with AD and this number …

Mild cognitive impairment: a concept in evolution

RC Petersen, B Caracciolo, C Brayne… - Journal of internal …, 2014 - Wiley Online Library
The construct of mild cognitive impairment (MCI) has evolved over the past 10 years since
the publication of the new MCI definition at the K ey S ymposium in 2003, but the core …

[HTML][HTML] Endogenous and exogenous estrogen exposures: how women's reproductive health can drive brain aging and inform Alzheimer's prevention

S Jett, N Malviya, E Schelbaum, G Jang… - Frontiers in Aging …, 2022 - frontiersin.org
After advanced age, female sex is the major risk factor for late-onset Alzheimer's disease
(AD), the most common cause of dementia affecting over 24 million people worldwide. The …

Classification and epidemiology of MCI

R Roberts, DS Knopman - Clinics in geriatric medicine, 2013 - geriatric.theclinics.com
Mild cognitive impairment (MCI) is the widely used term that describes an intermediate stage
from normal cognitive function to dementia. The concept of MCI is highly significant and …

Gender and incidence of dementia in the Framingham Heart Study from mid-adult life

G Chêne, A Beiser, R Au, SR Preis, PA Wolf… - Alzheimer's & …, 2015 - Elsevier
Background Gender-specific risks for dementia and Alzheimer's disease (AD) starting in
midlife remain largely unknown. Methods Prospectively ascertained dementia/AD and cause …

[HTML][HTML] The incidence of mild cognitive impairment: A systematic review and data synthesis

C Gillis, F Mirzaei, M Potashman, MA Ikram… - Alzheimer's & dementia …, 2019 - Elsevier
Introduction Incidence estimates of mild cognitive impairment (MCI) range widely. We
obtained contemporary age-specific MCI incidence rates and examined sources of …

Mild cognitive impairment: disparity of incidence and prevalence estimates

A Ward, HM Arrighi, S Michels, JM Cedarbaum - Alzheimer's & Dementia, 2012 - Elsevier
BACKGROUND: The purpose of conducting this study was to identify areas of concordance
and sources of variation for the published rates of prevalence and incidence associated with …

[HTML][HTML] Sex and gender driven modifiers of Alzheimer's: the role for estrogenic control across age, race, medical, and lifestyle risks

A Rahman, H Jackson, H Hristov… - Frontiers in aging …, 2019 - frontiersin.org
Research indicates that after advanced age, the major risk factor for late-onset Alzheimer's
disease is female sex. Out of every three AD patients, two are females with postmenopausal …

Baseline neuropsychiatric symptoms and the risk of incident mild cognitive impairment: a population-based study

YE Geda, RO Roberts, MM Mielke… - American Journal of …, 2014 - Am Psychiatric Assoc
Objective The authors conducted a prospective cohort study to estimate the risk of incident
mild cognitive impairment in cognitively normal elderly (aged≥ 70 years) individuals with or …