Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen and the
causative agent of blinding trachoma. Although Chlamydia is protected from humoral …

The intracellular life style of chlamydia and the ability to cause persistent infections with low-
grade replication requires tests with high analytical sensitivity to directly detect C …

Attempts to produce a vaccine to protect against Chlamydia trachomatis-induced trachoma
were initiated more than 100 years ago and continued for several decades. Using whole …

Hydrosalpinx induction in mice by Chlamydia muridarum infection, a model that has been
used to study C. trachomatis pathogenesis in women, is known to depend on the cryptic …

Chlamydia trachomatis is the leading cause of bacterial sexually transmitted disease
worldwide, and despite significant advances in chlamydial research, a prophylactic vaccine …

Blinding trachoma is an ancient neglected tropical disease caused by Chlamydia
trachomatis for which a vaccine is needed. We describe a live-attenuated vaccine that is …

Most Chlamydia species carry a 7.5 kb plasmid encoding eight open reading frames
conventionally called plasmid glycoproteins 1–8 or pGP1–8. Although the plasmid is not …

Genital Chlamydia trachomatis infection is the most commonly diagnosed sexually
transmitted infection. Trachoma is caused by ocular infection with C trachomatis and is the …

Chlamydia trachomatis (Ct) is an intracellular bacterial pathogen that relies on the activity of
secreted proteins known as effectors to promote replication and avoidance of immune …

Background Defining endpoints for trachoma programs can be a challenge as clinical signs
of infection may persist in the absence of detectable bacteria. Antibody-based tests may …