[HTML][HTML] Multi-Functional Characteristics of the Pseudomonas aeruginosa Type III Needle-Tip Protein, PcrV; Comparison to Orthologs in other Gram-negative Bacteria

H Sato, DW Frank - Frontiers in microbiology, 2011 - frontiersin.org
Pseudomonas aeruginosa possesses a type III secretion system (T3SS) to intoxicate host
cells and evade innate immunity. This virulence-related machinery consists of a molecular …

A re-evaluation of the role of B cells in protective immunity to Chlamydia infection

LX Li, SJ McSorley - Immunology letters, 2015 - Elsevier
Chlamydia trachomatis is the etiological agent of the most commonly reported bacterial
sexual transmitted infection (STI) in North America and Europe. The control of Chlamydia …

Chlamydia overcomes multiple gastrointestinal barriers to achieve long-lasting colonization

G Zhong - Trends in microbiology, 2021 - cell.com
Chlamydia trachomatis (CT) is frequently detected in the human gastrointestinal (GI) tract
despite its leading role in sexually transmitted bacterial infections in the genital tract …

National Institute of Allergy and Infectious Diseases workshop report:“Chlamydia vaccines: The way forward”

G Zhong, RC Brunham, LM de la Maza, T Darville… - Vaccine, 2019 - Elsevier
Chlamydia trachomatis (Ct), an intracellular pathogen, is the most common bacterial
sexually transmitted infection. In addition to acute cervicitis and urethritis, Ct can lead to …

Chlamydia spreading from the genital tract to the gastrointestinal tract–a two-hit hypothesis

G Zhong - Trends in microbiology, 2018 - cell.com
Chlamydia trachomatis, a leading bacterial cause of sexually transmitted infection-induced
infertility, is frequently detected in the gastrointestinal tract. Chlamydia muridarum, a model …

[HTML][HTML] Chlamydia trachomatis Pgp3 Antibody Persists and Correlates with Self-Reported Infection and Behavioural Risks in a Blinded Cohort Study

PJ Horner, GS Wills, A Righarts, S Vieira, D Kounali… - PLoS …, 2016 - journals.plos.org
Chlamydia trachomatis (Ct) serological studies in populations could help monitor changes in
lifetime cumulative risk of infection. We developed a double-antigen sandwich ELISA based …

Regulation of chlamydial infection by host autophagy and vacuolar ATPase-bearing organelles

M Yasir, ND Pachikara, X Bao, Z Pan… - Infection and …, 2011 - Am Soc Microbiol
As arguably the most successful parasite, Chlamydia is an obligate intracellular bacterium
replicating inside a vacuole of eukaryotic host cells. The chlamydial vacuole does not fuse …

[HTML][HTML] A novel synthetic peptide microarray assay detects Chlamydia species-specific antibodies in animal and human sera

K Sachse, KS Rahman, C Schnee, E Müller… - Scientific reports, 2018 - nature.com
Serological analysis of Chlamydia (C.) spp. infections is still mainly based on micro-
immunofluorescence and ELISA. To overcome the limitations of conventional serology, we …

Preclinical screen for protection efficacy of chlamydial antigens that are immunogenic in humans

C Lu, J Wang, G Zhong - Infection and immunity, 2023 - Am Soc Microbiol
To search for subunit vaccine candidates, immunogenic chlamydial antigens identified in
humans were evaluated for protection against both infection and pathology in a mouse …

[HTML][HTML] Chlamydia trachomatis Pgp3 Antibody Population Seroprevalence before and during an Era of Widespread Opportunistic Chlamydia Screening in England …

SC Woodhall, GS Wills, PJ Horner, R Craig, JS Mindell… - PloS one, 2017 - journals.plos.org
Background Opportunistic chlamydia screening of< 25 year-olds was nationally-
implemented in England in 2008 but its impact on chlamydia transmission is poorly …