Chlamydia trachomatis: Protective Adaptive Responses and Prospects for a Vaccine
TB Poston, T Darville - Biology of Chlamydia, 2018 - Springer
Chlamydia trachomatis is the most common cause of sexually transmitted bacterial infection
globally. These infections translate to a significant public health burden, particularly …
globally. These infections translate to a significant public health burden, particularly …
[HTML][HTML] Chlamydial plasmid-encoded virulence factor Pgp3 interacts with human cathelicidin peptide LL-37 to modulate immune response
S Hou, X Sun, X Dong, H Lin, L Tang, M Xue… - Microbes and …, 2019 - Elsevier
We have previously reported that Chlamydia trachomatis plasmid-encoded Pgp3 is able to
neutralize anti-chlamydial activity of human cathelicidin peptide LL-37 by binding to and …
neutralize anti-chlamydial activity of human cathelicidin peptide LL-37 by binding to and …
Protective immunity against mouse upper genital tract pathology correlates with high IFNγ but low IL-17 T cell and anti-secretion protein antibody responses induced …
C Lu, H Zeng, Z Li, L Lei, IT Yeh, Y Wu, G Zhong - Vaccine, 2012 - Elsevier
To search for optimal immunization conditions for inducing protective immunity against
upper genital tract pathologies caused by chlamydial intravaginal infection, we compared …
upper genital tract pathologies caused by chlamydial intravaginal infection, we compared …
[HTML][HTML] Structure of the Chlamydia trachomatis immunodominant antigen Pgp3
Chlamydia trachomatis infection is the most common sexually transmitted bacterial disease.
Left untreated, it can lead to ectopic pregnancy, pelvic inflammatory disease, and infertility …
Left untreated, it can lead to ectopic pregnancy, pelvic inflammatory disease, and infertility …
The Plasmid-Encoded pGP3 Promotes Chlamydia Evasion of Acidic Barriers in Both Stomach and Vagina
T Zhang, Z Huo, J Ma, C He, G Zhong - Infection and immunity, 2019 - Am Soc Microbiol
Although Chlamydia trachomatis is a human genital tract pathogen, chlamydial organisms
have frequently been detected in both vaginal and rectal swab samples of animals and …
have frequently been detected in both vaginal and rectal swab samples of animals and …
Comparison of the nine polymorphic membrane proteins of Chlamydia trachomatis for their ability to induce protective immune responses in mice against a C …
Objectives To test vaccines, formulated with novel antigens, to protect mice against
Chlamydia infections. Methods To determine the ability of polymorphic membrane proteins …
Chlamydia infections. Methods To determine the ability of polymorphic membrane proteins …
Subunit vaccines for the prevention of mucosal infection with Chlamydia trachomatis
H Yu, KP Karunakaran, X Jiang… - Expert review of …, 2016 - Taylor & Francis
Chlamydia trachomatis is the most common preventable cause of tubal infertility in women.
In high-income countries, despite public health control efforts, C. trachomatis case rates …
In high-income countries, despite public health control efforts, C. trachomatis case rates …
[HTML][HTML] Inadequate reference datasets biased toward short non-epitopes confound B-cell epitope prediction
X-ray crystallography has shown that an antibody paratope typically binds 15–22 amino
acids (aa) of an epitope, of which 2–5 randomly distributed amino acids contribute most of …
acids (aa) of an epitope, of which 2–5 randomly distributed amino acids contribute most of …
[HTML][HTML] Comparison of platforms for testing antibody responses against the Chlamydia trachomatis antigen Pgp3
S Gwyn, G Cooley, B Goodhew, S Kohlhoff… - The American Journal …, 2017 - ncbi.nlm.nih.gov
Antibody responses to Chlamydia trachomatis (CT) antigens may be useful tools for
surveillance of trachoma by estimating cumulative prevalence of infection within a …
surveillance of trachoma by estimating cumulative prevalence of infection within a …
[HTML][HTML] Immunogenicity and Protective Capacity of a Virus-like Particle Vaccine against Chlamydia trachomatis Type 3 Secretion System Tip Protein, CT584
E Webster, KW Seiger, SB Core, AL Collar… - Vaccines, 2022 - mdpi.com
An effective vaccine against Chlamydia trachomatis is urgently needed as infection rates
continue to rise and C. trachomatis causes reproductive morbidity. An obligate intracellular …
continue to rise and C. trachomatis causes reproductive morbidity. An obligate intracellular …