Application and prospects of butylphthalide for the treatment of neurologic diseases

XQ Chen, K Qiu, H Liu, Q He, JH Bai… - Chinese medical journal, 2019 - mednexus.org
Objective: The 3-N-butylphthalide (NBP) comprises one of the chemical constituents of
celery oil. It has a series of pharmacologic mechanisms including reconstructing …

[HTML][HTML] DL‑3‑n‑butylphthalide therapy for Parkinson's disease: A randomized controlled trial

H Zhou, M Ye, W Xu, M Yu… - Experimental and …, 2019 - spandidos-publications.com
Currently available treatments for Parkinson's disease (PD) do not delay or prevent disease
development and progression. DL‑3‑n‑butylphthalide (NBP), isolated from Apium …

The neuroprotective effect of Dl-3-n-butylphthalide in epileptic rats via inhibiting endoplasmic reticulum stress

S Tian, Z Qu, H Cao, X Niu, Q Qiao, B Zhang… - Folia …, 2023 - termedia.pl
Results: NBP 60 and NBP 120 decreased SRS frequency (all p< 0.05), shortened seizure
duration (all p< 0.05), and reduced the abnormal discharge of the brain. Nissl staining and …

A biophysical, minimal model to investigate age-related changes in CA1 pyramidal cell electrical activity

EC McKiernan, MA Herrera-Valdez, DF Marrone - bioRxiv, 2022 - biorxiv.org
Aging is a physiological process that is still poorly understood, especially with respect to
effects on the brain. There are open questions about aging that are difficult to answer with an …

[PDF][PDF] The therapeutic effect and mechanism of dl-3-n-butylphthalide in Alzheimer's disease

H Kong, H Chen, Y Fu, Y Dong, B Liu - INTERNATIONAL JOURNAL OF …, 2020 - e-century.us
Objective: To investigate the efficacy and mechanism of dl-3-n-butylphthalide in the
treatment of Alzheimer's disease. Methods: Ninety-six patients with Alzheimer's disease …