Cyclooxygenase (COX) enzymes comprise COX-1 and COX-2 isoforms and are responsible
for prostaglandin production. Prostaglandins have critical roles in the inflammation pathway …

Niclosamide is an oral antihelminthic drug used to treat parasitic infections in millions of
people worldwide. However recent studies have indicated that niclosamide may have broad …

Surgery, chemotherapy, radiotherapy, and hormone therapy are the main common anti-
tumor therapeutic approaches. However, the non-specific targeting of cancer cells has made …

The emergence of resistance to EGF receptor (EGFR) inhibitor therapy is a major clinical
problem for patients with non–small cell lung cancer (NSCLC). The mechanisms underlying …

The 'nanomedicine'approach has revolutionized cancer therapy by enabling the packaging
of therapeutic agents within engineered nanovehicles that can specifically accumulate …

Drug resistance represents a major challenge to achieving durable responses to cancer
therapeutics. Resistance mechanisms to epigenetically targeted drugs remain largely …

Chronic obstructive pulmonary disease (COPD) and lung cancer are frequently caused by
tobacco smoking. However, these diseases present opposite phenotypes involving redox …

The advent of targeted anticancer therapies over the past few decades has reinvigorated the
field of cancer therapeutics, with the promise of increased cancer cure rates accompanied …

Hyponatremia is frequently encountered in clinical practice and usually induced by renal
water retention. Many medications are considered to be among the various causes of …

The term 'nanomedicine'refers to the use of nanotechnology in the treatment, diagnosis and
monitoring of diseases. Magnetic drug targeting is a particularly promising application in this …