Animal models of kidney stone formation: an analysis
SR Khan - World journal of urology, 1997 - Springer
Calcific kidney stones in both humans and mildly hyperoxaluric rats are located on renal
papillary surfaces and consist of an organic matrix and crystals of calcium oxalate and/or …
papillary surfaces and consist of an organic matrix and crystals of calcium oxalate and/or …
Calcium oxalate crystal interaction with renal tubular epithelium, mechanism of crystal adhesion and its impact on stone development
SR Khan - Urological research, 1995 - Springer
The interaction between renal epithelial cells and calcium oxalate (CaOx) crystals and/or
oxalate ions plays a critical role in the formation of urinary stones. Epithelial cells respond to …
oxalate ions plays a critical role in the formation of urinary stones. Epithelial cells respond to …
Oxalate and calcium oxalate mediated free radical toxicity in renal epithelial cells: effect of antioxidants
S Thamilselvan, SR Khan, M Menon - Urological research, 2003 - Springer
In a previous study we demonstrated that oxalate induced free radical injury can promote
calcium oxalate stone formation. In the present study, we tested whether the antioxidants …
calcium oxalate stone formation. In the present study, we tested whether the antioxidants …
Lemon juice has protective activity in a rat urolithiasis model
M Touhami, A Laroubi, K Elhabazi, F Loubna, I Zrara… - BMC urology, 2007 - Springer
Background The use of herbal medicines (medicinal plants or phytotherapy) has recently
gained popularity in Europe and the United States. Nevertheless the exact mechanism of the …
gained popularity in Europe and the United States. Nevertheless the exact mechanism of the …
Ultrastructural immunodetection of osteopontin and osteocalcin as major matrix components of renal calculi
MD McKee, A Nancl, SR Khan - Journal of Bone and Mineral …, 1995 - academic.oup.com
The organic matrix of renal calculi has long been considered to influence the crystal growth
that occurs in these pathological mineral deposits. Recent advances in characterizing …
that occurs in these pathological mineral deposits. Recent advances in characterizing …
Renal calcinosis and stone formation in mice lacking osteopontin, Tamm-Horsfall protein, or both
L Mo, L Liaw, AP Evan, AJ Sommer… - American Journal of …, 2007 - journals.physiology.org
Although often supersaturated with mineral salts such as calcium phosphate and calcium
oxalate, normal urine possesses an innate ability to keep them from forming harmful crystals …
oxalate, normal urine possesses an innate ability to keep them from forming harmful crystals …
Renal tubular cell damage and oxidative stress in renal stone patients and the effect of potassium citrate treatment
K Tungsanga, P Sriboonlue, P Futrakul, C Yachantha… - Urological …, 2005 - Springer
Our objective was to evaluate the oxidative stress and renal tubular cell damage in patients
who have renal stones compared to normal subjects. The patients were re-evaluated after 1 …
who have renal stones compared to normal subjects. The patients were re-evaluated after 1 …
Crystal retention in renal stone disease: a crucial role for the glycosaminoglycan hyaluronan?
CF Verkoelen - Journal of the American Society of Nephrology, 2006 - journals.lww.com
The mechanisms that are involved in renal stone disease are not entirely clear. In this article,
the various concepts that have been proposed during the past century are reviewed briefly …
the various concepts that have been proposed during the past century are reviewed briefly …
Biopathological crystallization: a general view about the mechanisms of renal stone formation
F Grases, A Costa-Bauzá, L Garcıa-Ferragut - Advances in colloid and …, 1998 - Elsevier
A general classification of most common renal calculi (calcium oxalate, phosphate and uric
acid stones) based on their formation mechanism is presented. The main etiological factors …
acid stones) based on their formation mechanism is presented. The main etiological factors …
[PDF][PDF] Impact of ammonium chloride administration on a rat ethylene glycol urolithiasis model
J Fan, MA Glass, PS Chandhoke - Scanning Microsc, 1999 - ecmjournal.org
Ethylene glycol administration is a common method for the induction of experimental rat
urolithiasis. This drug has been used alone or in combination with other drugs such as …
urolithiasis. This drug has been used alone or in combination with other drugs such as …