Ethnopharmacological relevance Cannabis sativa L.(C. sativa) is an annual dioecious plant,
which shares its origins with the inception of the first agricultural human societies in Asia …

The medicinal use of Cannabis sativa L. can be traced back thousands of years to ancient
China and Egypt. While marijuana has recently shown promise in managing chronic pain …

Cannabis research has historically focused on the most prevalent cannabinoids. However,
extracts with a broad spectrum of secondary metabolites may have increased efficacy and …

Over the past years, several lines of evidence support a therapeutic potential of Cannabis
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …

For centuries, hashish and marihuana, both derived from the Indian hemp Cannabis sativa
L., have been used for their medicinal, as well as, their psychotropic effects. These effects …

Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

The golden age of cannabis pharmacology began in the 1960s as Raphael Mechoulam and
his colleagues in Israel isolated and synthesized cannabidiol, tetrahydrocannabinol, and …

The Cannabis sativa plant contains more than 120 cannabinoids. With the exceptions of∆ 9-
tetrahydrocannabinol (∆ 9-THC) and cannabidiol (CBD), comparatively little is known about …

Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

The endocannabinoid system is currently defined as the ensemble of the two 7-
transmembrane-domain and G protein-coupled receptors for Δ 9-tetrahydrocannabinol (but …