[HTML][HTML] Inflammation and tumor progression: signaling pathways and targeted intervention

H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

miRNAs insights into rheumatoid arthritis: Favorable and detrimental aspects of key performers

AS Doghish, A Ismail, HA El-Mahdy, SY Elkhawaga… - Life Sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) is a severe autoimmune inflammation that mostly affects the joints.
It's a multifactorial disease. Its clinical picture depends on genetic and epigenetic factors …

[HTML][HTML] Maresin1 protect against ferroptosis-induced liver injury through ROS inhibition and Nrf2/HO-1/GPX4 activation

W Yang, Y Wang, C Zhang, Y Huang, J Yu… - Frontiers in …, 2022 - frontiersin.org
Drugs, viruses, and chemical poisons stimulating live in a short period of time can cause
acute liver injury (ALI). ALI can further develop into serious liver diseases such as cirrhosis …

[HTML][HTML] Nanoenzyme engineered neutrophil-derived exosomes attenuate joint injury in advanced rheumatoid arthritis via regulating inflammatory environment

L Zhang, Z Qin, H Sun, X Chen, J Dong, S Shen… - Bioactive materials, 2022 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovitis and
destruction of cartilage, promoted by sustained inflammation. However, current treatments …

Glycine increased ferroptosis via SAM-mediated GPX4 promoter methylation in rheumatoid arthritis

H Ling, M Li, C Yang, S Sun, W Zhang, L Zhao… - …, 2022 - academic.oup.com
Objective Over-proliferation of synovium is a key event of invasive pannus formation and
cartilage damage in the progression of RA disease. At the same time, ferroptosis may play a …

[HTML][HTML] Phytochemicals as chemo-preventive agents and signaling molecule modulators: current role in cancer therapeutics and inflammation

MB Ahmed, SU Islam, AAA Alghamdi… - International Journal of …, 2022 - mdpi.com
Cancer is one of the deadliest non communicable diseases. Numerous anticancer
medications have been developed to target the molecular pathways driving cancer …

[HTML][HTML] Comprehensive overview of microRNA function in rheumatoid arthritis

X Peng, Q Wang, W Li, G Ge, J Peng, Y Xu, H Yang… - Bone Research, 2023 - nature.com
MicroRNAs (miRNAs), a class of endogenous single-stranded short noncoding RNAs, have
emerged as vital epigenetic regulators of both pathological and physiological processes in …

Quercetin-mediated SIRT1 activation attenuates collagen-induced mice arthritis

P Shen, W Lin, X Ba, Y Huang, Z Chen, L Han… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Herba taxilli (HT, Sangjisheng in Chinese), which is
composed of the dried stems and leaves of Taxillus chinensis (DC.) Danser, has been …

Maresin 1 alleviates dextran sulfate sodium-induced ulcerative colitis by regulating NRF2 and TLR4/NF-kB signaling pathway

S Qiu, P Li, H Zhao, X Li - International immunopharmacology, 2020 - Elsevier
Objective Ulcerative colitis (UC) is one of the most common gastrointestinal diseases,
characterized as a chronic, relapsing inflammation that causes damage to the colonic …

Milk microRNAs in health and disease

A Benmoussa, P Provost - … Reviews in food science and food …, 2019 - Wiley Online Library
MicroRNAs are small noncoding RNAs responsible for regulating 40% to 60% of gene
expression at the posttranscriptional level. The discovery of circulating microRNAs in several …