In-depth review of delivery carriers associated with vaccine adjuvants: current status and future perspectives

Y Zeng, F Zou, N Xia, S Li - Expert Review of Vaccines, 2023 - Taylor & Francis
Introduction Vaccines are powerful tools for controlling microbial infections and preventing
epidemics. To enhance the immune response to antigens, effective subunit vaccines or …

[HTML][HTML] Recent advances on the interaction of glycolipid and lipopeptide biosurfactants with model and biological membranes

FJ Aranda, JA Teruel, A Ortiz - Current Opinion in Colloid & Interface …, 2023 - Elsevier
Microbial biosurfactants have gained interest in the last decades because of their unique
characteristics. The variety of chemical structures within these compounds makes them very …

[HTML][HTML] Transferrin-functionalized liposomes loaded with vitamin VB12 for Alzheimer's disease therapy

S Andrade, MJ Ramalho, JA Loureiro… - International Journal of …, 2022 - Elsevier
Despite the efforts of the pharmaceutical and research sectors, Alzheimer's disease (AD)
remains incurable, imposing the demand for new effective strategies. Vitamin B12 (VB12) …

Drug delivery systems as a strategy to improve the efficacy of FDA-approved Alzheimer's drugs

D Nunes, JA Loureiro, MC Pereira - Pharmaceutics, 2022 - mdpi.com
Alzheimer's disease (AD) is the most common form of dementia, with a high impact
worldwide, accounting for more than 46 million cases. The continuous increase of AD …

[HTML][HTML] The effect of trans-resveratrol on the physicochemical properties of lipid membranes with different cholesterol content

Ł Płachta, M Mach, M Kowalska, P Wydro - Biochimica et Biophysica Acta …, 2024 - Elsevier
Resveratrol is one of the most popular phytoalexins, which naturally occurs in grapes and
red wine. This compound not only has beneficial effects on the human body, especially on …

Membrane permeability and antimicrobial peptides: Much more than just making a hole

JC Espeche, R Varas, P Maturana, AC Cutro… - Peptide …, 2024 - Wiley Online Library
Antimicrobial peptides (AMPs) are one of the elements of innate immunity that have a crucial
role in fighting infections. These molecules are produced by all kinds of cells and can …

Caffeic acid for the prevention and treatment of Alzheimer's disease: The effect of lipid membranes on the inhibition of aggregation and disruption of Aβ fibrils

S Andrade, JA Loureiro, MC Pereira - International Journal of Biological …, 2021 - Elsevier
The onset of Alzheimer's disease (AD) is triggered by the aggregation of amyloid β (Aβ)
peptides which leads to the formation of fibrils. Molecules that are able to inhibit fibrillation …

Analytical probing of membranotropic effects of antimicrobial copper nanoparticles on lipid vesicles as membrane models

M Izzi, M Oliver, H Mateos, G Palazzo, N Cioffi… - Nanoscale …, 2023 - pubs.rsc.org
Copper nanoparticles (CuNPs) are antimicrobial agents that are increasingly being used in
several real-life goods. However, concerns are arising about their potential toxicity and thus …

Mechanism study on nanoparticle negative surface charge modification by ascorbyl palmitate and its improvement of tumor targeting ability

L Li, H Wang, J Ye, Y Chen, R Wang, D Jin, Y Liu - Molecules, 2022 - mdpi.com
Surface charge polarity and density influence the immune clearance and cellular uptake of
intravenously administered lipid nanoparticles (LNPs), thus determining the efficiency of …

Multi-dose intravenous administration of neutral and cationic liposomes in mice: an extensive toxicity study

S Andrade, JA Loureiro, S Ramirez, CSG Catumbela… - Pharmaceuticals, 2022 - mdpi.com
Liposomes are widely used as delivery systems for therapeutic purposes. However, the
toxicity associated with the multi-dose administration of these nanoparticles is not fully …