NLRP3 inflammasome‐mediated pyroptosis is a proinflammatory programmed cell death
pathway, which plays a vital role in functional outcomes after stroke. We previously …

Neonatal hypoxic–ischaemic brain damage is a leading cause of child mortality and
morbidity, including cerebral palsy, epilepsy, and cognitive disabilities. The majority of …

Infection with SARs-COV-2 displays increasing fatality with age and underlying co-morbidity,
in particular, with markers of the metabolic syndrome and diabetes, which seems to be …

Background Neonatal hypoxic-ischemic brain injury (HIE) is caused by perinatal asphyxia,
which is associated with various confounding factors. Although studies on the pathogenesis …

Alzheimer's disease (AD) is the leading cause of dementia, affecting millions of people
worldwide. Oxidative stress contributes towards induction of neurodegeneration. It is one of …

Polyphenols are an important family of molecules of vegetal origin present in many
medicinal and edible plants, which represent important alimentary sources in the human …

Antioxidants are a class of molecules with an innate affinity to neutralize reactive oxygen
species (ROS), which are known to cause oxidative stress. Oxidative stress has been …

As human life expectancy increases, age-related health issues including neurodegenerative
diseases continue to rise. Regardless of genetic or environmental factors, many …

Cerebrovascular diseases are currently a major global health problem. Considering the
limitations of current therapy, the search for new alternatives for the treatment of these …

Background Cardiac fibrosis is a pathological process characterized by excess extracellular
matrix (ECM) deposition and plays a critical role in nearly all types of heart disease. The …